Lange T - Search Results

1

Detection of mutant free circulating tumor DNA in the plasma of patients with gastrointestinal stromal tumor harboring activating mutations of CKIT or PDGFRA.

Maier J, Lange T, Kerle I, Specht K, Bruegel M, Wickenhauser C, Jost P, Niederwieser D, Peschel C, Duyster J, von Bubnoff N. Maier J, et al. Among authors: lange t. Clin Cancer Res. 2013 Sep 1;19(17):4854-67. doi: 10.1158/1078-0432.CCR-13-0765. Epub 2013 Jul 5. Clin Cancer Res. 2013. PMID: 23833305 Clinical Trial.

2

Circulating cKIT and PDGFRA DNA indicates disease activity in Gastrointestinal Stromal Tumor (GIST).

Jilg S, Rassner M, Maier J, Waldeck S, Kehl V, Follo M, Philipp U, Sauter A, Specht K, Mitschke J, Lange T, Bauer S, Jost PJ, Peschel C, Duyster J, Gaiser T, Hohenberger P, von Bubnoff N. Jilg S, et al. Among authors: lange t. Int J Cancer. 2019 Oct 15;145(8):2292-2303. doi: 10.1002/ijc.32282. Epub 2019 Apr 29. Int J Cancer. 2019. PMID: 30882891 Free article. Clinical Trial.

3

High incidence of BCR-ABL kinase domain mutations and absence of mutations of the PDGFR and KIT activation loops in CML patients with secondary resistance to imatinib.

Al-Ali HK, Heinrich MC, Lange T, Krahl R, Mueller M, Müller C, Niederwieser D, Druker BJ, Deininger MW. Al-Ali HK, et al. Among authors: lange t. Hematol J. 2004;5(1):55-60. doi: 10.1038/sj.thj.6200319. Hematol J. 2004. PMID: 14745431

4

Allele-specific wild-type blocker quantitative PCR for highly sensitive detection of rare JAK2 p.V617F point mutation in primary myelofibrosis as an appropriate tool for the monitoring of molecular remission following therapy.

Siebolts U, Lange T, Niederwieser D, Wickenhauser C. Siebolts U, et al. Among authors: lange t. J Clin Pathol. 2010 Apr;63(4):370-2. doi: 10.1136/jcp.2009.069773. J Clin Pathol. 2010. PMID: 20354212

5

JAK2 p.V617F allele burden in myeloproliferative neoplasms one month after allogeneic stem cell transplantation significantly predicts outcome and risk of relapse.

Lange T, Edelmann A, Siebolts U, Krahl R, Nehring C, Jäkel N, Cross M, Maier J, Niederwieser D, Wickenhauser C. Lange T, et al. Haematologica. 2013 May;98(5):722-8. doi: 10.3324/haematol.2012.076901. Epub 2013 Jan 8. Haematologica. 2013. PMID: 23300178 Free PMC article.

6

A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy after failure of imatinib.

Ernst T, Gruber FX, Pelz-Ackermann O, Maier J, Pfirrmann M, Müller MC, Mikkola I, Porkka K, Niederwieser D, Hochhaus A, Lange T. Ernst T, et al. Among authors: lange t. Haematologica. 2009 Sep;94(9):1227-35. doi: 10.3324/haematol.2009.006981. Epub 2009 Jul 16. Haematologica. 2009. PMID: 19608684 Free PMC article. Clinical Trial.

7

Optimized Digital Droplet PCR for BCR-ABL.

Maier J, Lange T, Cross M, Wildenberger K, Niederwieser D, Franke GN. Maier J, et al. Among authors: lange t. J Mol Diagn. 2019 Jan;21(1):27-37. doi: 10.1016/j.jmoldx.2018.08.012. Epub 2018 Oct 19. J Mol Diagn. 2019. PMID: 30347270 Free article.

8

Comparison of Real-Time Quantitative PCR and Digital Droplet PCR for BCR-ABL1 Monitoring in Patients with Chronic Myeloid Leukemia.

Franke GN, Maier J, Wildenberger K, Cross M, Giles FJ, Müller MC, Hochhaus A, Niederwieser D, Lange T. Franke GN, et al. Among authors: lange t. J Mol Diagn. 2020 Jan;22(1):81-89. doi: 10.1016/j.jmoldx.2019.08.007. Epub 2019 Oct 24. J Mol Diagn. 2020. PMID: 31669230 Free article.

9

The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia.

Lange T, Ernst T, Gruber FX, Maier J, Cross M, Müller MC, Niederwieser D, Hochhaus A, Pfirrmann M. Lange T, et al. Haematologica. 2013 May;98(5):714-7. doi: 10.3324/haematol.2012.068890. Epub 2012 Oct 12. Haematologica. 2013. PMID: 23065514 Free PMC article.

10

JAK2V617F molecular remission in a primary myelofibrosis patient treated with ruxolitinib.

Koehler A, Hubert K, Lange T, Siebolts U, Wickenhauser C, Gopalakrishna P, Niederwieser D, Monecke A, Al-Ali HK. Koehler A, et al. Among authors: lange t. Ann Hematol. 2015 Nov;94(11):1929-30. doi: 10.1007/s00277-015-2454-4. Epub 2015 Jul 23. Ann Hematol. 2015. PMID: 26202608 No abstract available.

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