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Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic β-cell function over 5 years of follow-up.
Andersson EA, Allin KH, Sandholt CH, Borglykke A, Lau CJ, Ribel-Madsen R, Sparsø T, Justesen JM, Harder MN, Jørgensen ME, Jørgensen T, Hansen T, Pedersen O. Andersson EA, et al. Among authors: jorgensen t, jorgensen me. Diabetes. 2013 Oct;62(10):3610-7. doi: 10.2337/db13-0362. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835328 Free PMC article. Clinical Trial.
Combined analyses of 20 common obesity susceptibility variants.
Sandholt CH, Sparsø T, Grarup N, Albrechtsen A, Almind K, Hansen L, Toft U, Jørgensen T, Hansen T, Pedersen O. Sandholt CH, et al. Among authors: jorgensen t. Diabetes. 2010 Jul;59(7):1667-73. doi: 10.2337/db09-1042. Epub 2010 Jan 28. Diabetes. 2010. PMID: 20110568 Free PMC article. Clinical Trial.
MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.
Andersson EA, Holst B, Sparsø T, Grarup N, Banasik K, Holmkvist J, Jørgensen T, Borch-Johnsen K, Egerod KL, Lauritzen T, Sørensen TI, Bonnefond A, Meyre D, Froguel P, Schwartz TW, Pedersen O, Hansen T. Andersson EA, et al. Among authors: jorgensen t. Diabetes. 2010 Jun;59(6):1539-48. doi: 10.2337/db09-1757. Epub 2010 Mar 3. Diabetes. 2010. PMID: 20200315 Free PMC article.
Studies of metabolic phenotypic correlates of 15 obesity associated gene variants.
Sandholt CH, Vestmar MA, Bille DS, Borglykke A, Almind K, Hansen L, Sandbæk A, Lauritzen T, Witte D, Jørgensen T, Pedersen O, Hansen T. Sandholt CH, et al. Among authors: jorgensen t. PLoS One. 2011;6(9):e23531. doi: 10.1371/journal.pone.0023531. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912638 Free PMC article.
The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.
Andersson EA, Harder MN, Pilgaard K, Pisinger C, Stančáková A, Kuusisto J, Grarup N, Færch K, Poulsen P, Witte DR, Jørgensen T, Vaag A, Laakso M, Pedersen O, Hansen T. Andersson EA, et al. Among authors: jorgensen t. PLoS One. 2011;6(11):e27096. doi: 10.1371/journal.pone.0027096. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22073261 Free PMC article.
Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk.
Marquez M, Huyvaert M, Perry JR, Pearson RD, Falchi M, Morris AP, Vivequin S, Lobbens S, Yengo L, Gaget S, Pattou F, Poulain-Godefroy O, Charpentier G, Carlsson LM, Jacobson P, Sjöström L, Lantieri O, Heude B, Walley A, Balkau B, Marre M, Froguel P, Cauchi S; DIAGRAM Consortium. Marquez M, et al. Diabetes. 2012 Feb;61(2):524-30. doi: 10.2337/db11-0728. Epub 2011 Dec 30. Diabetes. 2012. PMID: 22210315 Free PMC article.
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tönjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, Rasmussen-Torvik LJ, Stringham HM, Tanaka T, Aadahl M, Arking DE, Bergmann S, Boerwinkle E, Bonnycastle LL, Bornstein SR, Brunner E, Bumpstead SJ, Brage S, Carlson OD, Chen H, Chen YD, Chines PS, Collins FS, Couper DJ, Dennison EM, Dowling NF, Egan JS, Ekelund U, Erdos MR, Forouhi NG, Fox CS, Goodarzi MO, Grässler J, Gustafsson S, Hallmans G, Hansen T, Hingorani A, Holloway JW, Hu FB, Isomaa B, Jameson KA, Johansson I, Jonsson A, Jørgensen T, Kivimaki M, Kovacs P, Kumari M, Kuusisto J, Laakso M, Lecoeur C, Lévy-Marchal C, Li G, Loos RJ, Lyssenko V, Marmot M, Marques-Vidal P, Morken MA, Müller G, North KE, Pankow JS, Payne F, Prokopenko I, Psaty BM, Renström F, Rice K, Rotter JI, Rybin D, Sandholt CH, Sayer AA, Shrader P, Schwarz PE, Siscovick DS, Stancáková A, Stumvoll M, Teslovich TM, Waeber G, Williams GH, Witte DR, Wood AR, Xie W, Boehnke M, Cooper C, Ferrucci L, Froguel P, Groop L, Kao WH, Vollenweider P, Walker M, Watanabe RM, Pedersen O, Meigs JB, Ingelsson E, Barroso I, Florez JC, Franks PW, Dupuis J, Wareh… See abstract for full author list ➔ Scott RA, et al. Among authors: jorgensen t. Diabetes. 2012 May;61(5):1291-6. doi: 10.2337/db11-0973. Epub 2012 Mar 13. Diabetes. 2012. PMID: 22415877 Free PMC article.
Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.
Harder MN, Ribel-Madsen R, Justesen JM, Sparsø T, Andersson EA, Grarup N, Jørgensen T, Linneberg A, Hansen T, Pedersen O. Harder MN, et al. Among authors: jorgensen t. J Clin Endocrinol Metab. 2013 Apr;98(4):E801-6. doi: 10.1210/jc.2012-4169. Epub 2013 Mar 1. J Clin Endocrinol Metab. 2013. PMID: 23457408
1,810 results