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A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.
Rad R, Cadiñanos J, Rad L, Varela I, Strong A, Kriegl L, Constantino-Casas F, Eser S, Hieber M, Seidler B, Price S, Fraga MF, Calvanese V, Hoffman G, Ponstingl H, Schneider G, Yusa K, Grove C, Schmid RM, Wang W, Vassiliou G, Kirchner T, McDermott U, Liu P, Saur D, Bradley A. Rad R, et al. Among authors: fraga mf. Cancer Cell. 2013 Jul 8;24(1):15-29. doi: 10.1016/j.ccr.2013.05.014. Cancer Cell. 2013. PMID: 23845441 Free PMC article.
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Mueller S, Engleitner T, Maresch R, Zukowska M, Lange S, Kaltenbacher T, Konukiewitz B, Öllinger R, Zwiebel M, Strong A, Yen HY, Banerjee R, Louzada S, Fu B, Seidler B, Götzfried J, Schuck K, Hassan Z, Arbeiter A, Schönhuber N, Klein S, Veltkamp C, Friedrich M, Rad L, Barenboim M, Ziegenhain C, Hess J, Dovey OM, Eser S, Parekh S, Constantino-Casas F, de la Rosa J, Sierra MI, Fraga M, Mayerle J, Klöppel G, Cadiñanos J, Liu P, Vassiliou G, Weichert W, Steiger K, Enard W, Schmid RM, Yang F, Unger K, Schneider G, Varela I, Bradley A, Saur D, Rad R. Mueller S, et al. Nature. 2018 Feb 1;554(7690):62-68. doi: 10.1038/nature25459. Epub 2018 Jan 24. Nature. 2018. PMID: 29364867 Free PMC article.
SirT1 brings stemness closer to cancer and aging.
Calvanese V, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Aging (Albany NY). 2011 Feb;3(2):162-7. doi: 10.18632/aging.100272. Aging (Albany NY). 2011. PMID: 21307403 Free PMC article.
Epigenetics of embryonic stem cells.
Calvanese V, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Adv Exp Med Biol. 2012;741:231-53. doi: 10.1007/978-1-4614-2098-9_16. Adv Exp Med Biol. 2012. PMID: 22457114
Epigenetic code and self-identity.
Calvanese V, Lara E, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Adv Exp Med Biol. 2012;738:236-55. doi: 10.1007/978-1-4614-1680-7_14. Adv Exp Med Biol. 2012. PMID: 22399383 Review.
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer.
Lara E, Calvanese V, Huidobro C, Fernández AF, Moncada-Pazos A, Obaya AJ, Aguilera O, González-Sancho JM, Sánchez L, Astudillo A, Muñoz A, López-Otín C, Esteller M, Fraga MF. Lara E, et al. Among authors: fraga mf. Mol Cancer. 2010 Jun 30;9:170. doi: 10.1186/1476-4598-9-170. Mol Cancer. 2010. PMID: 20591152 Free PMC article.
The role of epigenetics in aging and age-related diseases.
Calvanese V, Lara E, Kahn A, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Ageing Res Rev. 2009 Oct;8(4):268-76. doi: 10.1016/j.arr.2009.03.004. Epub 2009 Apr 1. Ageing Res Rev. 2009. PMID: 19716530 Review.
A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer.
Huidobro C, Urdinguio RG, Rodríguez RM, Mangas C, Calvanese V, Martínez-Camblor P, Ferrero C, Parra-Blanco A, Rodrigo L, Obaya AJ, Suárez-Fernández L, Astudillo A, Hernando H, Ballestar E, Fernández AF, Fraga MF. Huidobro C, et al. Among authors: fraga mf. Eur J Cancer. 2012 Sep;48(14):2270-81. doi: 10.1016/j.ejca.2011.12.019. Epub 2012 Jan 13. Eur J Cancer. 2012. PMID: 22244828
306 results