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Randomised phase II trial of gemcitabine and nab-paclitaxel with necuparanib or placebo in untreated metastatic pancreas ductal adenocarcinoma.
O'Reilly EM, Barone D, Mahalingam D, Bekaii-Saab T, Shao SH, Wolf J, Rosano M, Krause S, Richards DA, Yu KH, Roach JM, Flaherty KT, Ryan DP. O'Reilly EM, et al. Among authors: roach jm. Eur J Cancer. 2020 Jun;132:112-121. doi: 10.1016/j.ejca.2020.03.005. Epub 2020 Apr 28. Eur J Cancer. 2020. PMID: 32361265 Free PMC article. Clinical Trial.
Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR. Bhatt AP, et al. Among authors: roach jm. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7374-7381. doi: 10.1073/pnas.1918095117. Epub 2020 Mar 13. Proc Natl Acad Sci U S A. 2020. PMID: 32170007 Free PMC article.
40 results