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A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
Psychosis Endophenotypes International Consortium; Wellcome Trust Case-Control Consortium 2; Bramon E, Pirinen M, Strange A, Lin K, Freeman C, Bellenguez C, Su Z, Band G, Pearson R, Vukcevic D, Langford C, Deloukas P, Hunt S, Gray E, Dronov S, Potter SC, Tashakkori-Ghanbaria A, Edkins S, Bumpstead SJ, Arranz MJ, Bakker S, Bender S, Bruggeman R, Cahn W, Chandler D, Collier DA, Crespo-Facorro B, Dazzan P, de Haan L, Di Forti M, Dragović M, Giegling I, Hall J, Iyegbe C, Jablensky A, Kahn RS, Kalaydjieva L, Kravariti E, Lawrie S, Linszen DH, Mata I, McDonald C, McIntosh A, Myin-Germeys I, Ophoff RA, Pariante CM, Paunio T, Picchioni M; Psychiatric Genomics Consortium; Ripke S, Rujescu D, Sauer H, Shaikh M, Sussmann J, Suvisaari J, Tosato S, Toulopoulou T, Van Os J, Walshe M, Weisbrod M, Whalley H, Wiersma D, Blackwell JM, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski JA, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Wood NW, Barroso I, Peltonen L, Lewis CM, Murray RM, Donnelly P, Powell J, Spencer CC. Psychosis Endophenotypes International Consortium, et al. Among authors: chandler d. Biol Psychiatry. 2014 Mar 1;75(5):386-97. doi: 10.1016/j.biopsych.2013.03.033. Epub 2013 Jul 17. Biol Psychiatry. 2014. PMID: 23871474 Free PMC article.
Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia.
Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM, Judge R, Smith DJ, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Dwyer S, O'Donoghue T, Morar B, Cooper M, Chandler D, Jablensky A, Gill M, Kaladjieva L, Morris DW, O'Donovan MC, Rujescu D, Donohoe G. Walters JT, et al. Among authors: chandler d. Arch Gen Psychiatry. 2010 Jul;67(7):692-700. doi: 10.1001/archgenpsychiatry.2010.81. Arch Gen Psychiatry. 2010. PMID: 20603450
Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes.
Peters K, Wiltshire S, Henders AK, Dragović M, Badcock JC, Chandler D, Howell S, Ellis C, Bouwer S, Montgomery GW, Palmer LJ, Kalaydjieva L, Jablensky A. Peters K, et al. Among authors: chandler d. Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5;147B(7):1159-66. doi: 10.1002/ajmg.b.30741. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18314870
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia.
Chandler D, Dragović M, Cooper M, Badcock JC, Mullin BH, Faulkner D, Wilson SG, Hallmayer J, Howell S, Rock D, Palmer LJ, Kalaydjieva L, Jablensky A. Chandler D, et al. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):428-437. doi: 10.1002/ajmg.b.30996. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 19569075
Deleterious GRM1 mutations in schizophrenia.
Ayoub MA, Angelicheva D, Vile D, Chandler D, Morar B, Cavanaugh JA, Visscher PM, Jablensky A, Pfleger KD, Kalaydjieva L. Ayoub MA, et al. Among authors: chandler d. PLoS One. 2012;7(3):e32849. doi: 10.1371/journal.pone.0032849. Epub 2012 Mar 20. PLoS One. 2012. PMID: 22448230 Free PMC article.
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia.
Jablensky A, Angelicheva D, Donohoe GJ, Cruickshank M, Azmanov DN, Morris DW, McRae A, Weickert CS, Carter KW, Chandler D, Alexandrov B, Usheva A, Morar B, Verbrugghe PL, Filipovska A, Rackham O, Bishop AR, Rasmussen KØ, Dragovic M, Cooper M, Phillips M, Badcock J, Bramon-Bosch E, Almeida OP, Flicker L, Gill M, Corvin A, MacGregor S, Kalaydjieva L. Jablensky A, et al. Among authors: chandler d. Mol Psychiatry. 2012 Dec;17(12):1328-39. doi: 10.1038/mp.2011.129. Epub 2011 Oct 4. Mol Psychiatry. 2012. PMID: 21968932
Impact of the Reelin signaling cascade (ligands-receptors-adaptor complex) on cognition in schizophrenia.
Verbrugghe P, Bouwer S, Wiltshire S, Carter K, Chandler D, Cooper M, Morar B, Razif MF, Henders A, Badcock JC, Dragovic M, Carr V, Almeida OP, Flicker L, Montgomery G, Jablensky A, Kalaydjieva L. Verbrugghe P, et al. Among authors: chandler d. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun;159B(4):392-404. doi: 10.1002/ajmg.b.32042. Epub 2012 Mar 14. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22419519
861 results