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Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.
Ansari M, McKeigue PM, Skerka C, Hayward C, Rudan I, Vitart V, Polasek O, Armbrecht AM, Yates JR, Vatavuk Z, Bencic G, Kolcic I, Oostra BA, Van Duijn CM, Campbell S, Stanton CM, Huffman J, Shu X, Khan JC, Shahid H, Harding SP, Bishop PN, Deary IJ, Moore AT, Dhillon B, Rudan P, Zipfel PF, Sim RB, Hastie ND, Campbell H, Wright AF. Ansari M, et al. Among authors: sim rb. Hum Mol Genet. 2013 Dec 1;22(23):4857-69. doi: 10.1093/hmg/ddt336. Epub 2013 Jul 19. Hum Mol Genet. 2013. PMID: 23873044 Free PMC article.
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells.
Sjöberg AP, Trouw LA, Clark SJ, Sjölander J, Heinegård D, Sim RB, Day AJ, Blom AM. Sjöberg AP, et al. Among authors: sim rb. J Biol Chem. 2007 Apr 13;282(15):10894-900. doi: 10.1074/jbc.M610256200. Epub 2007 Feb 9. J Biol Chem. 2007. PMID: 17293598 Free article.
Heterogeneity of MBL-MASP complexes.
Mayilyan KR, Presanis JS, Arnold JN, Hajela K, Sim RB. Mayilyan KR, et al. Among authors: sim rb. Mol Immunol. 2006 Mar;43(8):1286-92. doi: 10.1016/j.molimm.2005.07.011. Epub 2005 Aug 15. Mol Immunol. 2006. PMID: 16102832
314 results