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Page 1
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.
Azizan EA, Poulsen H, Tuluc P, Zhou J, Clausen MV, Lieb A, Maniero C, Garg S, Bochukova EG, Zhao W, Shaikh LH, Brighton CA, Teo AE, Davenport AP, Dekkers T, Tops B, Küsters B, Ceral J, Yeo GS, Neogi SG, McFarlane I, Rosenfeld N, Marass F, Hadfield J, Margas W, Chaggar K, Solar M, Deinum J, Dolphin AC, Farooqi IS, Striessnig J, Nissen P, Brown MJ. Azizan EA, et al. Among authors: clausen mv. Nat Genet. 2013 Sep;45(9):1055-60. doi: 10.1038/ng.2716. Epub 2013 Aug 4. Nat Genet. 2013. PMID: 23913004
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, Sansom MS, Tucker SJ, Carpenter EP. Dong YY, et al. Among authors: clausen mv. Science. 2015 Mar 13;347(6227):1256-9. doi: 10.1126/science.1261512. Science. 2015. PMID: 25766236 Free PMC article.
Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.
Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike ACW, Carpenter EP, Baukrowitz T, Sansom MSP, Tucker SJ. Aryal P, et al. Among authors: clausen mv. Structure. 2017 May 2;25(5):708-718.e2. doi: 10.1016/j.str.2017.03.006. Epub 2017 Apr 6. Structure. 2017. PMID: 28392258 Free PMC article.
Asymmetric mechanosensitivity in a eukaryotic ion channel.
Clausen MV, Jarerattanachat V, Carpenter EP, Sansom MSP, Tucker SJ. Clausen MV, et al. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8343-E8351. doi: 10.1073/pnas.1708990114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923939 Free PMC article.