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GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm.
Bottolo L, Chadeau-Hyam M, Hastie DI, Zeller T, Liquet B, Newcombe P, Yengo L, Wild PS, Schillert A, Ziegler A, Nielsen SF, Butterworth AS, Ho WK, Castagné R, Munzel T, Tregouet D, Falchi M, Cambien F, Nordestgaard BG, Fumeron F, Tybjærg-Hansen A, Froguel P, Danesh J, Petretto E, Blankenberg S, Tiret L, Richardson S. Bottolo L, et al. PLoS Genet. 2013;9(8):e1003657. doi: 10.1371/journal.pgen.1003657. Epub 2013 Aug 8. PLoS Genet. 2013. PMID: 23950726 Free PMC article.
Variability of the Human Serum Metabolome over 3 Months in the EXPOsOMICS Personal Exposure Monitoring Study.
Oosterwegel MJ, Ibi D, Portengen L, Probst-Hensch N, Tarallo S, Naccarati A, Imboden M, Jeong A, Robinot N, Scalbert A, Amaral AFS, van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vermeulen R, Keski-Rahkonen P, Vlaanderen J. Oosterwegel MJ, et al. Environ Sci Technol. 2023 Aug 29;57(34):12752-12759. doi: 10.1021/acs.est.3c03233. Epub 2023 Aug 15. Environ Sci Technol. 2023. PMID: 37582220 Free PMC article.
Sequence-level population simulations over large genomic regions.
Hoggart CJ, Chadeau-Hyam M, Clark TG, Lampariello R, Whittaker JC, De Iorio M, Balding DJ. Hoggart CJ, et al. Genetics. 2007 Nov;177(3):1725-31. doi: 10.1534/genetics.106.069088. Epub 2007 Oct 18. Genetics. 2007. PMID: 17947444 Free PMC article.
Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation.
Guida F, Sandanger TM, Castagné R, Campanella G, Polidoro S, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Severi G, Kyrtopoulos SA, Georgiadis P, Vermeulen RC, Lund E, Vineis P, Chadeau-Hyam M. Guida F, et al. Hum Mol Genet. 2015 Apr 15;24(8):2349-59. doi: 10.1093/hmg/ddu751. Epub 2015 Jan 2. Hum Mol Genet. 2015. PMID: 25556184 Free PMC article.
Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome.
Castagné R, Kelly-Irving M, Campanella G, Guida F, Krogh V, Palli D, Panico S, Sacerdote C, Tumino R, Kleinjans J, de Kok T, Kyrtopoulos SA, Lang T, Stringhini S, Vermeulen R, Vineis P, Delpierre C, Chadeau-Hyam M. Castagné R, et al. Sci Rep. 2016 Dec 9;6:38705. doi: 10.1038/srep38705. Sci Rep. 2016. PMID: 27934951 Free PMC article. Clinical Trial.
A multivariate approach to investigate the combined biological effects of multiple exposures.
Jain P, Vineis P, Liquet B, Vlaanderen J, Bodinier B, van Veldhoven K, Kogevinas M, Athersuch TJ, Font-Ribera L, Villanueva CM, Vermeulen R, Chadeau-Hyam M. Jain P, et al. J Epidemiol Community Health. 2018 Jul;72(7):564-571. doi: 10.1136/jech-2017-210061. Epub 2018 Mar 21. J Epidemiol Community Health. 2018. PMID: 29563153 Free PMC article.
157 results