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Canonical Wnt signaling negatively modulates regulatory T cell function.
van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ. van Loosdregt J, et al. Among authors: van boxtel r, van es jh. Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954131 Free article.
Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.
van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, van Beekum O, Brenkman AB, Hijnen DJ, Mutis T, Kalkhoven E, Prakken BJ, Coffer PJ. van Loosdregt J, et al. Among authors: van beekum o. Blood. 2010 Feb 4;115(5):965-74. doi: 10.1182/blood-2009-02-207118. Epub 2009 Dec 7. Blood. 2010. PMID: 19996091 Free article.
Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells.
Wehrens EJ, Mijnheer G, Duurland CL, Klein M, Meerding J, van Loosdregt J, de Jager W, Sawitzki B, Coffer PJ, Vastert B, Prakken BJ, van Wijk F. Wehrens EJ, et al. Among authors: van loosdregt j, van wijk f. Blood. 2011 Sep 29;118(13):3538-48. doi: 10.1182/blood-2010-12-328187. Epub 2011 Aug 9. Blood. 2011. PMID: 21828127 Free article.
Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.
Gao Y, Koppen A, Rakhshandehroo M, Tasdelen I, van de Graaf SF, van Loosdregt J, van Beekum O, Hamers N, van Leenen D, Berkers CR, Berger R, Holstege FC, Coffer PJ, Brenkman AB, Ovaa H, Kalkhoven E. Gao Y, et al. Among authors: van loosdregt j, van de graaf sf, van leenen d, van beekum o. Nat Commun. 2013;4:2656. doi: 10.1038/ncomms3656. Nat Commun. 2013. PMID: 24141283 Free article.
A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples.
Spreafico R, Rossetti M, van den Broek T, Jansen NJ, Zhang H, Moshref M, Prakken B, van Loosdregt J, van Wijk F, Albani S. Spreafico R, et al. Among authors: van loosdregt j, van den broek t, van wijk f. Eur J Immunol. 2014 Oct;44(10):3141-3. doi: 10.1002/eji.201444627. Epub 2014 Aug 25. Eur J Immunol. 2014. PMID: 25042685 Free article. No abstract available.
47 results