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Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. Lu D, et al. Among authors: dearmond sj. J Pharmacol Exp Ther. 2013 Nov;347(2):325-38. doi: 10.1124/jpet.113.205799. Epub 2013 Aug 21. J Pharmacol Exp Ther. 2013. PMID: 23965382 Free PMC article.
Human prion strain selection in transgenic mice.
Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. Giles K, et al. Among authors: dearmond sj. Ann Neurol. 2010 Aug;68(2):151-61. doi: 10.1002/ana.22104. Ann Neurol. 2010. PMID: 20695008 Free PMC article.
Chimeric elk/mouse prion proteins in transgenic mice.
Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. Tamgüney G, et al. Among authors: dearmond sj. J Gen Virol. 2013 Feb;94(Pt 2):443-452. doi: 10.1099/vir.0.045989-0. Epub 2012 Oct 24. J Gen Virol. 2013. PMID: 23100369 Free PMC article.
Drug resistance confounding prion therapeutics.
Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. Berry DB, et al. Among authors: dearmond sj. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4160-9. doi: 10.1073/pnas.1317164110. Epub 2013 Oct 15. Proc Natl Acad Sci U S A. 2013. PMID: 24128760 Free PMC article.
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. Giles K, et al. Among authors: dearmond sj. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12. doi: 10.1124/jpet.115.224659. Epub 2015 Jul 29. J Pharmacol Exp Ther. 2015. PMID: 26224882 Free PMC article.
Convergent replication of mouse synthetic prion strains.
Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Ghaemmaghami S, et al. Among authors: dearmond sj. Am J Pathol. 2013 Mar;182(3):866-74. doi: 10.1016/j.ajpath.2012.11.038. Am J Pathol. 2013. PMID: 23438476 Free PMC article.
263 results