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106 results

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Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. Lu D, et al. Among authors: oehler a. J Pharmacol Exp Ther. 2013 Nov;347(2):325-38. doi: 10.1124/jpet.113.205799. Epub 2013 Aug 21. J Pharmacol Exp Ther. 2013. PMID: 23965382 Free PMC article.
Spontaneous generation of anchorless prions in transgenic mice.
Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. Stöhr J, et al. Among authors: oehler a. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21223-8. doi: 10.1073/pnas.1117827108. Epub 2011 Dec 12. Proc Natl Acad Sci U S A. 2011. PMID: 22160704 Free PMC article.
Protease-resistant prions selectively decrease Shadoo protein.
Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. Watts JC, et al. Among authors: oehler a. PLoS Pathog. 2011 Nov;7(11):e1002382. doi: 10.1371/journal.ppat.1002382. Epub 2011 Nov 17. PLoS Pathog. 2011. PMID: 22163178 Free PMC article.
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions.
Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. Stöhr J, et al. Among authors: oehler a. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):11025-30. doi: 10.1073/pnas.1206555109. Epub 2012 Jun 18. Proc Natl Acad Sci U S A. 2012. PMID: 22711819 Free PMC article.
Chimeric elk/mouse prion proteins in transgenic mice.
Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. Tamgüney G, et al. Among authors: oehler a. J Gen Virol. 2013 Feb;94(Pt 2):443-452. doi: 10.1099/vir.0.045989-0. Epub 2012 Oct 24. J Gen Virol. 2013. PMID: 23100369 Free PMC article.
Convergent replication of mouse synthetic prion strains.
Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Ghaemmaghami S, et al. Among authors: oehler a. Am J Pathol. 2013 Mar;182(3):866-74. doi: 10.1016/j.ajpath.2012.11.038. Am J Pathol. 2013. PMID: 23438476 Free PMC article.
Drug resistance confounding prion therapeutics.
Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. Berry DB, et al. Among authors: oehler a. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4160-9. doi: 10.1073/pnas.1317164110. Epub 2013 Oct 15. Proc Natl Acad Sci U S A. 2013. PMID: 24128760 Free PMC article.
106 results