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Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, Räikkönen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Völzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothw… See abstract for full author list ➔ Sabater-Lleal M, et al. Among authors: illig t. Circulation. 2013 Sep 17;128(12):1310-24. doi: 10.1161/CIRCULATIONAHA.113.002251. Epub 2013 Aug 22. Circulation. 2013. PMID: 23969696 Free PMC article.
Common variants in myocardial ion channel genes modify the QT interval in the general population: results from the KORA study.
Pfeufer A, Jalilzadeh S, Perz S, Mueller JC, Hinterseer M, Illig T, Akyol M, Huth C, Schöpfer-Wendels A, Kuch B, Steinbeck G, Holle R, Näbauer M, Wichmann HE, Meitinger T, Kääb S. Pfeufer A, et al. Among authors: illig t. Circ Res. 2005 Apr 1;96(6):693-701. doi: 10.1161/01.RES.0000161077.53751.e6. Epub 2005 Mar 3. Circ Res. 2005. PMID: 15746444
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O'Donnell CJ, Hirschhorn JN, Kääb S, Spooner PM, Meitinger T, Chakravarti A. Arking DE, et al. Among authors: illig t. Nat Genet. 2006 Jun;38(6):644-51. doi: 10.1038/ng1790. Epub 2006 Apr 30. Nat Genet. 2006. PMID: 16648850
SNP-based analysis of genetic substructure in the German population.
Steffens M, Lamina C, Illig T, Bettecken T, Vogler R, Entz P, Suk EK, Toliat MR, Klopp N, Caliebe A, König IR, Köhler K, Ludemann J, Diaz Lacava A, Fimmers R, Lichtner P, Ziegler A, Wolf A, Krawczak M, Nūrnberg P, Hampe J, Schreiber S, Meitinger T, Wichmann HE, Roeder K, Wienker TF, Baur MP. Steffens M, et al. Among authors: illig t. Hum Hered. 2006;62(1):20-9. doi: 10.1159/000095850. Epub 2006 Sep 21. Hum Hered. 2006. PMID: 17003564
Lymphotoxin-alpha and galectin-2 SNPs are not associated with myocardial infarction in two different German populations.
Sedlacek K, Neureuther K, Mueller JC, Stark K, Fischer M, Baessler A, Reinhard W, Broeckel U, Lieb W, Erdmann J, Schunkert H, Riegger G, Illig T, Meitinger T, Hengstenberg C. Sedlacek K, et al. Among authors: illig t. J Mol Med (Berl). 2007 Sep;85(9):997-1004. doi: 10.1007/s00109-007-0211-4. Epub 2007 May 12. J Mol Med (Berl). 2007. PMID: 17497114
Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case-Cohort Study, 1984-2002.
Herder C, Klopp N, Baumert J, Müller M, Khuseyinova N, Meisinger C, Martin S, Illig T, Koenig W, Thorand B. Herder C, et al. Among authors: illig t. Diabetologia. 2008 Feb;51(2):276-84. doi: 10.1007/s00125-007-0800-3. Epub 2007 Aug 22. Diabetologia. 2008. PMID: 17712545
Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study).
Holzapfel C, Klopp N, Grallert H, Huth C, Gieger C, Meisinger C, Strassburger K, Giani G, Wichmann HE, Laumen H, Hauner H, Herder C, Rathmann W, Illig T. Holzapfel C, et al. Among authors: illig t. Eur J Endocrinol. 2007 Sep;157(3):R1-5. doi: 10.1530/EJE-07-0297. Eur J Endocrinol. 2007. PMID: 17766704
697 results