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Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species.
Cominacini L, Pasini AF, Garbin U, Davoli A, Tosetti ML, Campagnola M, Rigoni A, Pastorino AM, Lo Cascio V, Sawamura T. Cominacini L, et al. Among authors: sawamura t. J Biol Chem. 2000 Apr 28;275(17):12633-8. doi: 10.1074/jbc.275.17.12633. J Biol Chem. 2000. PMID: 10777555 Free article.
The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide.
Cominacini L, Rigoni A, Pasini AF, Garbin U, Davoli A, Campagnola M, Pastorino AM, Lo Cascio V, Sawamura T. Cominacini L, et al. Among authors: sawamura t. J Biol Chem. 2001 Apr 27;276(17):13750-5. doi: 10.1074/jbc.M010612200. Epub 2001 Jan 24. J Biol Chem. 2001. PMID: 11278710 Free article.
An endothelial receptor for oxidized low-density lipoprotein.
Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T. Sawamura T, et al. Nature. 1997 Mar 6;386(6620):73-7. doi: 10.1038/386073a0. Nature. 1997. PMID: 9052782
454 results