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Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions.
Hasegawa M, Fujiwara H, Nonaka T, Wakabayashi K, Takahashi H, Lee VM, Trojanowski JQ, Mann D, Iwatsubo T. Hasegawa M, et al. J Biol Chem. 2002 Dec 13;277(50):49071-6. doi: 10.1074/jbc.M208046200. Epub 2002 Oct 10. J Biol Chem. 2002. PMID: 12377775 Free article.
alpha-Synuclein is one of the major components of intracellular fibrillary aggregates in the brains of a subset of neurodegenerative disorders, including Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and Hallervorden-Spatz disease, which are referred to …
alpha-Synuclein is one of the major components of intracellular fibrillary aggregates in the brains of a subset of neurodegenerative disorde …
TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.
Davidson Y, Amin H, Kelley T, Shi J, Tian J, Kumaran R, Lashley T, Lees AJ, DuPlessis D, Neary D, Snowden J, Akiyama H, Arai T, Hasegawa M, Bandopadhyay R, Sikkink S, Pickering-Brown S, Mann DM. Davidson Y, et al. Among authors: hasegawa m. Acta Neuropathol. 2009 Sep;118(3):359-69. doi: 10.1007/s00401-009-0526-z. Epub 2009 Mar 28. Acta Neuropathol. 2009. PMID: 19330339
Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration.
Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM. Foulds PG, et al. Among authors: hasegawa m. Acta Neuropathol. 2009 Nov;118(5):647-58. doi: 10.1007/s00401-009-0594-0. Epub 2009 Oct 13. Acta Neuropathol. 2009. PMID: 19823856 Free PMC article.
Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Tsuji H, Nonaka T, Yamashita M, Masuda-Suzukake M, Kametani F, Akiyama H, Mann DM, Tamaoka A, Hasegawa M. Tsuji H, et al. Among authors: hasegawa m. Biochem Biophys Res Commun. 2012 Jan 6;417(1):116-21. doi: 10.1016/j.bbrc.2011.11.066. Epub 2011 Nov 22. Biochem Biophys Res Commun. 2012. PMID: 22133678
Phosphorylated α-synuclein in Parkinson's disease.
Wang Y, Shi M, Chung KA, Zabetian CP, Leverenz JB, Berg D, Srulijes K, Trojanowski JQ, Lee VM, Siderowf AD, Hurtig H, Litvan I, Schiess MC, Peskind ER, Masuda M, Hasegawa M, Lin X, Pan C, Galasko D, Goldstein DS, Jensen PH, Yang H, Cain KC, Zhang J. Wang Y, et al. Among authors: hasegawa m. Sci Transl Med. 2012 Feb 15;4(121):121ra20. doi: 10.1126/scitranslmed.3002566. Sci Transl Med. 2012. PMID: 22344688 Free PMC article.
4,137 results