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The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.
Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA; Alzheimer's Disease Neuroimaging Initiative; Genetic and Environmental Risk for Alzheimer's Disease Consortium GERAD; Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C. Benitez BA, et al. Among authors: goate am. PLoS Genet. 2013;9(8):e1003685. doi: 10.1371/journal.pgen.1003685. Epub 2013 Aug 22. PLoS Genet. 2013. PMID: 23990795 Free PMC article.
Molecular genetics of Alzheimer's disease.
Clark RF, Goate AM. Clark RF, et al. Among authors: goate am. Arch Neurol. 1993 Nov;50(11):1164-72. doi: 10.1001/archneur.1993.00540110044004. Arch Neurol. 1993. PMID: 8215975 Review.
Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.
Berg L, McKeel DW Jr, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM, Price JL, Gearing M, Mirra SS, Saunders AM. Berg L, et al. Among authors: goate am. Arch Neurol. 1998 Mar;55(3):326-35. doi: 10.1001/archneur.55.3.326. Arch Neurol. 1998. PMID: 9520006
397 results