Hickson ID - Search Results

1

Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.

Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ. Rosenthal AS, et al. Among authors: hickson id. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5660-6. doi: 10.1016/j.bmcl.2013.08.025. Epub 2013 Aug 13. Bioorg Med Chem Lett. 2013. PMID: 24012121 Free PMC article.

2

The Bloom's syndrome gene product is a 3'-5' DNA helicase.

Karow JK, Chakraverty RK, Hickson ID. Karow JK, et al. Among authors: hickson id. J Biol Chem. 1997 Dec 5;272(49):30611-4. doi: 10.1074/jbc.272.49.30611. J Biol Chem. 1997. PMID: 9388193 Free article.

3

Oligomeric ring structure of the Bloom's syndrome helicase.

Karow JK, Newman RH, Freemont PS, Hickson ID. Karow JK, et al. Among authors: hickson id. Curr Biol. 1999 Jun 3;9(11):597-600. doi: 10.1016/s0960-9822(99)80264-4. Curr Biol. 1999. PMID: 10359700 Free article.

4

The Bloom's syndrome gene product interacts with topoisomerase III.

Wu L, Davies SL, North PS, Goulaouic H, Riou JF, Turley H, Gatter KC, Hickson ID. Wu L, et al. Among authors: hickson id. J Biol Chem. 2000 Mar 31;275(13):9636-44. doi: 10.1074/jbc.275.13.9636. J Biol Chem. 2000. PMID: 10734115 Free article.

5

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity.

Brosh RM Jr, Li JL, Kenny MK, Karow JK, Cooper MP, Kureekattil RP, Hickson ID, Bohr VA. Brosh RM Jr, et al. Among authors: hickson id. J Biol Chem. 2000 Aug 4;275(31):23500-8. doi: 10.1074/jbc.M001557200. J Biol Chem. 2000. PMID: 10825162 Free article.

6

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51.

Wu L, Davies SL, Levitt NC, Hickson ID. Wu L, et al. Among authors: hickson id. J Biol Chem. 2001 Jun 1;276(22):19375-81. doi: 10.1074/jbc.M009471200. Epub 2001 Feb 8. J Biol Chem. 2001. PMID: 11278509 Free article.

7

Role of the Bloom's syndrome helicase in maintenance of genome stability.

Hickson ID, Davies SL, Li JL, Levitt NC, Mohaghegh P, North PS, Wu L. Hickson ID, et al. Biochem Soc Trans. 2001 May;29(Pt 2):201-4. doi: 10.1042/0300-5127:0290201. Biochem Soc Trans. 2001. PMID: 11356154 Review.

8

The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells.

Turley H, Wu L, Canamero M, Gatter KC, Hickson ID. Turley H, et al. Among authors: hickson id. Br J Cancer. 2001 Jul 20;85(2):261-5. doi: 10.1054/bjoc.2001.1874. Br J Cancer. 2001. PMID: 11461087 Free PMC article.

9

Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands.

Li JL, Harrison RJ, Reszka AP, Brosh RM Jr, Bohr VA, Neidle S, Hickson ID. Li JL, et al. Among authors: hickson id. Biochemistry. 2001 Dec 18;40(50):15194-202. doi: 10.1021/bi011067h. Biochemistry. 2001. PMID: 11735402

10

Premature aging in RecQ helicase-deficient human syndromes.

Mohaghegh P, Hickson ID. Mohaghegh P, et al. Among authors: hickson id. Int J Biochem Cell Biol. 2002 Nov;34(11):1496-501. doi: 10.1016/s1357-2725(02)00039-0. Int J Biochem Cell Biol. 2002. PMID: 12200042 Review.

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