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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM. Ryan KJ, et al. Among authors: kaskow bj. Sci Transl Med. 2017 Dec 20;9(421):eaai7635. doi: 10.1126/scitranslmed.aai7635. Sci Transl Med. 2017. PMID: 29263232 Free PMC article.
Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.
Roostaei T, Klein HU, Ma Y, Felsky D, Kivisäkk P, Connor SM, Kroshilina A, Yung C, Kaskow BJ, Shao X, Rhead B, Ordovás JM, Absher DM, Arnett DK, Liu J, Patsopoulos N, Barcellos LF, Weiner HL, De Jager PL. Roostaei T, et al. Among authors: kaskow bj. Nat Commun. 2021 Dec 6;12(1):7078. doi: 10.1038/s41467-021-27427-w. Nat Commun. 2021. PMID: 34873174 Free PMC article.
MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells.
Kaskow BJ, Buttrick TS, Klein HU, White C, Bourgeois JR, Ferland RJ, Patsopoulos N, Bradshaw EM, De Jager PL, Elyaman W. Kaskow BJ, et al. Neurol Neuroimmunol Neuroinflamm. 2017 Dec 8;5(1):e414. doi: 10.1212/NXI.0000000000000414. eCollection 2018 Jan. Neurol Neuroimmunol Neuroinflamm. 2017. PMID: 29379820 Free PMC article.
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL. Klein HU, et al. Among authors: kaskow bj. Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559478 Free PMC article.
Effector T Cells in Multiple Sclerosis.
Kaskow BJ, Baecher-Allan C. Kaskow BJ, et al. Cold Spring Harb Perspect Med. 2018 Apr 2;8(4):a029025. doi: 10.1101/cshperspect.a029025. Cold Spring Harb Perspect Med. 2018. PMID: 29358315 Free PMC article. Review.
Multiple Sclerosis: Mechanisms and Immunotherapy.
Baecher-Allan C, Kaskow BJ, Weiner HL. Baecher-Allan C, et al. Among authors: kaskow bj. Neuron. 2018 Feb 21;97(4):742-768. doi: 10.1016/j.neuron.2018.01.021. Neuron. 2018. PMID: 29470968 Free article. Review.
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