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Page 1
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.
Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K. Pemovska T, et al. Among authors: ellonen p. Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20. Cancer Discov. 2013. PMID: 24056683
Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.
Mononen N, Seppälä EH, Duggal P, Autio V, Ikonen T, Ellonen P, Saharinen J, Saarela J, Vihinen M, Tammela TL, Kallioniemi O, Bailey-Wilson JE, Schleutker J. Mononen N, et al. Among authors: ellonen p. Cancer Res. 2006 Jan 15;66(2):743-7. doi: 10.1158/0008-5472.CAN-05-1723. Cancer Res. 2006. PMID: 16424004
No evidence for shared etiology in two demyelinative disorders, MS and PLOSL.
Sulonen AM, Kallio SP, Ellonen P, Suvela M, Elovaara I, Koivisto K, Pirttilä T, Reunanen M, Tienari PJ, Palotie A, Peltonen L, Saarela J. Sulonen AM, et al. Among authors: ellonen p. J Neuroimmunol. 2009 Jan 3;206(1-2):86-90. doi: 10.1016/j.jneuroim.2008.10.005. Epub 2008 Nov 18. J Neuroimmunol. 2009. PMID: 19019460 Free PMC article.
Comparison of solution-based exome capture methods for next generation sequencing.
Sulonen AM, Ellonen P, Almusa H, Lepistö M, Eldfors S, Hannula S, Miettinen T, Tyynismaa H, Salo P, Heckman C, Joensuu H, Raivio T, Suomalainen A, Saarela J. Sulonen AM, et al. Among authors: ellonen p. Genome Biol. 2011 Sep 28;12(9):R94. doi: 10.1186/gb-2011-12-9-r94. Genome Biol. 2011. PMID: 21955854 Free PMC article.
Somatic STAT3 mutations in large granular lymphocytic leukemia.
Koskela HL, Eldfors S, Ellonen P, van Adrichem AJ, Kuusanmäki H, Andersson EI, Lagström S, Clemente MJ, Olson T, Jalkanen SE, Majumder MM, Almusa H, Edgren H, Lepistö M, Mattila P, Guinta K, Koistinen P, Kuittinen T, Penttinen K, Parsons A, Knowles J, Saarela J, Wennerberg K, Kallioniemi O, Porkka K, Loughran TP Jr, Heckman CA, Maciejewski JP, Mustjoki S. Koskela HL, et al. Among authors: ellonen p. N Engl J Med. 2012 May 17;366(20):1905-13. doi: 10.1056/NEJMoa1114885. N Engl J Med. 2012. PMID: 22591296 Free PMC article.
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS.
Tuononen K, Mäki-Nevala S, Sarhadi VK, Wirtanen A, Rönty M, Salmenkivi K, Andrews JM, Telaranta-Keerie AI, Hannula S, Lagström S, Ellonen P, Knuuttila A, Knuutila S. Tuononen K, et al. Among authors: ellonen p. Genes Chromosomes Cancer. 2013 May;52(5):503-11. doi: 10.1002/gcc.22047. Epub 2013 Jan 30. Genes Chromosomes Cancer. 2013. PMID: 23362162
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.
Rajala HL, Eldfors S, Kuusanmäki H, van Adrichem AJ, Olson T, Lagström S, Andersson EI, Jerez A, Clemente MJ, Yan Y, Zhang D, Awwad A, Ellonen P, Kallioniemi O, Wennerberg K, Porkka K, Maciejewski JP, Loughran TP Jr, Heckman C, Mustjoki S. Rajala HL, et al. Among authors: ellonen p. Blood. 2013 May 30;121(22):4541-50. doi: 10.1182/blood-2012-12-474577. Epub 2013 Apr 17. Blood. 2013. PMID: 23596048 Free PMC article.
Mutated ephrin receptor genes in non-small cell lung carcinoma and their occurrence with driver mutations-targeted resequencing study on formalin-fixed, paraffin-embedded tumor material of 81 patients.
Mäki-Nevala S, Kaur Sarhadi V, Tuononen K, Lagström S, Ellonen P, Rönty M, Wirtanen A, Knuuttila A, Knuutila S. Mäki-Nevala S, et al. Among authors: ellonen p. Genes Chromosomes Cancer. 2013 Dec;52(12):1141-9. doi: 10.1002/gcc.22109. Epub 2013 Oct 7. Genes Chromosomes Cancer. 2013. PMID: 24123310
77 results