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Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.
Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K. Pemovska T, et al. Among authors: gjertsen bt. Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20. Cancer Discov. 2013. PMID: 24056683
Release of angiopoietin-1 by primary human acute myelogenous leukemia cells is associated with mutations of nucleophosmin, increased by bone marrow stromal cells and possibly antagonized by high systemic angiopoietin-2 levels.
Hatfield KJ, Hovland R, Øyan AM, Kalland KH, Ryningen A, Gjertsen BT, Bruserud Ø. Hatfield KJ, et al. Among authors: gjertsen bt. Leukemia. 2008 Feb;22(2):287-93. doi: 10.1038/sj.leu.2404985. Epub 2007 Oct 18. Leukemia. 2008. PMID: 17943167
Review: genetic models of acute myeloid leukaemia.
McCormack E, Bruserud O, Gjertsen BT. McCormack E, et al. Among authors: gjertsen bt. Oncogene. 2008 Jun 19;27(27):3765-79. doi: 10.1038/onc.2008.16. Epub 2008 Feb 11. Oncogene. 2008. PMID: 18264136 Review.
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines.
Bredholt T, Dimba EA, Hagland HR, Wergeland L, Skavland J, Fossan KO, Tronstad KJ, Johannessen AC, Vintermyr OK, Gjertsen BT. Bredholt T, et al. Among authors: gjertsen bt. Mol Cancer. 2009 Nov 13;8:101. doi: 10.1186/1476-4598-8-101. Mol Cancer. 2009. PMID: 19912650 Free PMC article.
Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status--consequences and potentials for pharmacological intervention.
Reikvam H, Hatfield KJ, Ersvaer E, Hovland R, Skavland J, Gjertsen BT, Petersen K, Bruserud O. Reikvam H, et al. Among authors: gjertsen bt. Br J Haematol. 2012 Feb;156(4):468-80. doi: 10.1111/j.1365-2141.2011.08960.x. Epub 2011 Dec 13. Br J Haematol. 2012. PMID: 22150087 Free article.
281 results