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IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW. Pellegrini M, et al. Cell. 2011 Feb 18;144(4):601-13. doi: 10.1016/j.cell.2011.01.011. Epub 2011 Feb 3. Cell. 2011. PMID: 21295337 Free article.
IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.
Croker BA, Kiu H, Pellegrini M, Toe J, Preston S, Metcalf D, O'Donnell JA, Cengia LH, McArthur K, Nicola NA, Alexander WS, Roberts AW. Croker BA, et al. Among authors: pellegrini m. Immunol Cell Biol. 2012 Jan;90(1):124-9. doi: 10.1038/icb.2011.29. Epub 2011 Apr 26. Immunol Cell Biol. 2012. PMID: 21519345 Free PMC article.
ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system.
Lin AE, Ebert G, Ow Y, Preston SP, Toe JG, Cooney JP, Scott HW, Sasaki M, Saibil SD, Dissanayake D, Kim RH, Wakeham A, You-Ten A, Shahinian A, Duncan G, Silvester J, Ohashi PS, Mak TW, Pellegrini M. Lin AE, et al. Among authors: pellegrini m. Nat Immunol. 2013 Jan;14(1):27-33. doi: 10.1038/ni.2478. Epub 2012 Nov 25. Nat Immunol. 2013. PMID: 23179078
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.
Masters SL, Gerlic M, Metcalf D, Preston S, Pellegrini M, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, Hilton DJ, Alexander WS, Kile BT, Croker BA. Masters SL, et al. Among authors: pellegrini m. Immunity. 2012 Dec 14;37(6):1009-23. doi: 10.1016/j.immuni.2012.08.027. Epub 2012 Dec 6. Immunity. 2012. PMID: 23219391 Free PMC article.
1,671 results