Cvijic ME - Search Results

1

Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research.

Tang H, Shen DR, Han YH, Kong Y, Balimane P, Marino A, Gao M, Wu S, Xie D, Soars MG, O'Connell JC, Rodrigues AD, Zhang L, Cvijic ME. Tang H, et al. Among authors: cvijic me. J Biomol Screen. 2013 Oct;18(9):1072-83. doi: 10.1177/1087057113494807. J Biomol Screen. 2013. PMID: 24062352

2

384-Well Multiplexed Luminex Cytokine Assays for Lead Optimization.

Tang H, Panemangalore R, Yarde M, Zhang L, Cvijic ME. Tang H, et al. Among authors: cvijic me. J Biomol Screen. 2016 Jul;21(6):548-55. doi: 10.1177/1087057116644164. Epub 2016 Apr 19. J Biomol Screen. 2016. PMID: 27095819

3

Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists.

Zhu Y, Watson J, Chen M, Shen DR, Yarde M, Agler M, Burford N, Alt A, Jayachandra S, Cvijic ME, Zhang L, Dyckman A, Xie J, O'Connell J, Banks M, Weston A. Zhu Y, et al. Among authors: cvijic me. J Biomol Screen. 2014 Aug;19(7):1079-89. doi: 10.1177/1087057114533146. Epub 2014 Apr 30. J Biomol Screen. 2014. PMID: 24789006

4

A high-content glucocorticoid receptor translocation assay for compound mechanism-of-action evaluation.

Agler M, Prack M, Zhu Y, Kolb J, Nowak K, Ryseck R, Shen D, Cvijic ME, Somerville J, Nadler S, Chen T. Agler M, et al. Among authors: cvijic me. J Biomol Screen. 2007 Dec;12(8):1029-41. doi: 10.1177/1087057107309353. Epub 2007 Nov 7. J Biomol Screen. 2007. PMID: 17989426

5

Drug-induced perturbations of the bile acid pool, cholestasis, and hepatotoxicity: mechanistic considerations beyond the direct inhibition of the bile salt export pump.

Rodrigues AD, Lai Y, Cvijic ME, Elkin LL, Zvyaga T, Soars MG. Rodrigues AD, et al. Among authors: cvijic me. Drug Metab Dispos. 2014 Apr;42(4):566-74. doi: 10.1124/dmd.113.054205. Epub 2013 Oct 10. Drug Metab Dispos. 2014. PMID: 24115749 Review.

6

High-throughput high-content imaging assays for identification and characterization of selective AXL pathway inhibitors.

Tang H, Yang J, Shen DR, Calambur D, Witmer M, Wu S, Carpenter B, Zhang Y, Gao M, Constantine K, Zhang L, Cvijic ME. Tang H, et al. Among authors: cvijic me. Assay Drug Dev Technol. 2014 Jan-Feb;12(1):80-6. doi: 10.1089/adt.2013.540. Assay Drug Dev Technol. 2014. PMID: 24547742

7

GPCR profiling: from hits to leads and from genotype to phenotype.

Cvijic ME, Sum CS, Alt A, Zhang L. Cvijic ME, et al. Drug Discov Today Technol. 2015 Nov;18:30-7. doi: 10.1016/j.ddtec.2015.10.005. Epub 2015 Nov 6. Drug Discov Today Technol. 2015. PMID: 26723890 Review.

8

Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series.

Watterson SH, Guo J, Spergel SH, Langevine CM, Moquin RV, Shen DR, Yarde M, Cvijic ME, Banas D, Liu R, Suchard SJ, Gillooly K, Taylor T, Rex-Rabe S, Shuster DJ, McIntyre KW, Cornelius G, D'Arienzo C, Marino A, Balimane P, Warrack B, Salter-Cid L, McKinnon M, Barrish JC, Carter PH, Pitts WJ, Xie J, Dyckman AJ. Watterson SH, et al. Among authors: cvijic me. J Med Chem. 2016 Mar 24;59(6):2820-40. doi: 10.1021/acs.jmedchem.6b00089. Epub 2016 Mar 10. J Med Chem. 2016. PMID: 26924461

9

Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1).

Guo J, Watterson SH, Spergel SH, Kempson J, Langevine CM, Shen DR, Yarde M, Cvijic ME, Banas D, Liu R, Suchard SJ, Gillooly K, Taylor T, Rex-Rabe S, Shuster DJ, McIntyre KW, Cornelius G, D'Arienzo C, Marino A, Balimane P, Salter-Cid L, McKinnon M, Barrish JC, Carter PH, Pitts WJ, Xie J, Dyckman AJ. Guo J, et al. Among authors: cvijic me. Bioorg Med Chem Lett. 2016 May 15;26(10):2470-2474. doi: 10.1016/j.bmcl.2016.03.105. Epub 2016 Apr 1. Bioorg Med Chem Lett. 2016. PMID: 27055941

10

Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P₁ Receptor Modulator.

Yang MG, Xiao Z, Dhar TG, Xiao HY, Gilmore JL, Marcoux D, Xie JH, McIntyre KW, Taylor TL, Borowski V, Heimrich E, Li YW, Feng J, Fernandes A, Yang Z, Balimane P, Marino AM, Cornelius G, Warrack BM, Mathur A, Wu DR, Li P, Gupta A, Pragalathan B, Shen DR, Cvijic ME, Lehman-McKeeman LD, Salter-Cid L, Barrish JC, Carter PH, Dyckman AJ. Yang MG, et al. Among authors: cvijic me. J Med Chem. 2016 Dec 22;59(24):11138-11147. doi: 10.1021/acs.jmedchem.6b01433. Epub 2016 Dec 7. J Med Chem. 2016. PMID: 28002964

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