Rodrigues AD - Search Results

1

Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research.

Tang H, Shen DR, Han YH, Kong Y, Balimane P, Marino A, Gao M, Wu S, Xie D, Soars MG, O'Connell JC, Rodrigues AD, Zhang L, Cvijic ME. Tang H, et al. Among authors: rodrigues ad. J Biomol Screen. 2013 Oct;18(9):1072-83. doi: 10.1177/1087057113494807. J Biomol Screen. 2013. PMID: 24062352

2

Pharmacokinetic drug interactions involving 17alpha-ethinylestradiol: a new look at an old drug.

Zhang H, Cui D, Wang B, Han YH, Balimane P, Yang Z, Sinz M, Rodrigues AD. Zhang H, et al. Among authors: rodrigues ad. Clin Pharmacokinet. 2007;46(2):133-57. doi: 10.2165/00003088-200746020-00003. Clin Pharmacokinet. 2007. PMID: 17253885 Review.

3

Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.

Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD. Han YH, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2010 Jul;38(7):1072-82. doi: 10.1124/dmd.109.031518. Epub 2010 Apr 1. Drug Metab Dispos. 2010. PMID: 20360302

4

Drug-induced perturbations of the bile acid pool, cholestasis, and hepatotoxicity: mechanistic considerations beyond the direct inhibition of the bile salt export pump.

Rodrigues AD, Lai Y, Cvijic ME, Elkin LL, Zvyaga T, Soars MG. Rodrigues AD, et al. Drug Metab Dispos. 2014 Apr;42(4):566-74. doi: 10.1124/dmd.113.054205. Epub 2013 Oct 10. Drug Metab Dispos. 2014. PMID: 24115749 Review.

5

Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.

Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD. Han YH, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2010 Jul;38(7):1064-71. doi: 10.1124/dmd.109.031526. Epub 2010 Apr 1. Drug Metab Dispos. 2010. PMID: 20360303

6

Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes.

Chen C, Han YH, Yang Z, Rodrigues AD. Chen C, et al. Among authors: rodrigues ad. Xenobiotica. 2011 Jun;41(6):476-85. doi: 10.3109/00498254.2011.560971. Epub 2011 Mar 7. Xenobiotica. 2011. PMID: 21381897

7

Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation.

Shen H, Yang Z, Mintier G, Han YH, Chen C, Balimane P, Jemal M, Zhao W, Zhang R, Kallipatti S, Selvam S, Sukrutharaj S, Krishnamurthy P, Marathe P, Rodrigues AD. Shen H, et al. Among authors: rodrigues ad. J Pharmacol Exp Ther. 2013 Mar;344(3):673-85. doi: 10.1124/jpet.112.200691. Epub 2013 Jan 7. J Pharmacol Exp Ther. 2013. PMID: 23297161

8

Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro.

Zhang Y, Han YH, Putluru SP, Matta MK, Kole P, Mandlekar S, Furlong MT, Liu T, Iyer RA, Marathe P, Yang Z, Lai Y, Rodrigues AD. Zhang Y, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2016 Mar;44(3):320-8. doi: 10.1124/dmd.115.066944. Epub 2015 Dec 29. Drug Metab Dispos. 2016. PMID: 26714763

9

Cynomolgus Monkey as an Emerging Animal Model to Study Drug Transporters: In Vitro, In Vivo, In Vitro-to-In Vivo Translation.

Shen H, Yang Z, Rodrigues AD. Shen H, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2022 Mar;50(3):299-319. doi: 10.1124/dmd.121.000695. Epub 2021 Dec 10. Drug Metab Dispos. 2022. PMID: 34893475 Review.

10

1-Aminobenzotriazole, a known cytochrome P450 inhibitor, is a substrate and inhibitor of N-acetyltransferase.

Sun Q, Harper TW, Dierks EA, Zhang L, Chang S, Rodrigues AD, Marathe P. Sun Q, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2011 Sep;39(9):1674-9. doi: 10.1124/dmd.111.039834. Epub 2011 Jun 15. Drug Metab Dispos. 2011. PMID: 21677062

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