Tomlinson IP - Search Results

1

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer.

Domingo E, Church DN, Sieber O, Ramamoorthy R, Yanagisawa Y, Johnstone E, Davidson B, Kerr DJ, Tomlinson IP, Midgley R. Domingo E, et al. Among authors: tomlinson ip. J Clin Oncol. 2013 Dec 1;31(34):4297-305. doi: 10.1200/JCO.2013.50.0322. Epub 2013 Sep 23. J Clin Oncol. 2013. PMID: 24062397 Clinical Trial.

2

The mutation rate and cancer.

Tomlinson IP, Novelli MR, Bodmer WF. Tomlinson IP, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14800-3. doi: 10.1073/pnas.93.25.14800. Proc Natl Acad Sci U S A. 1996. PMID: 8962135 Free PMC article.

3

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.

Sieber OM, Tomlinson IP, Lamlum H. Sieber OM, et al. Among authors: tomlinson ip. Mol Med Today. 2000 Dec;6(12):462-9. doi: 10.1016/s1357-4310(00)01828-1. Mol Med Today. 2000. PMID: 11099951 Review.

4

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.

Sieber OM, Heinimann K, Gorman P, Lamlum H, Crabtree M, Simpson CA, Davies D, Neale K, Hodgson SV, Roylance RR, Phillips RK, Bodmer WF, Tomlinson IP. Sieber OM, et al. Among authors: tomlinson ip. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16910-5. doi: 10.1073/pnas.012679099. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486240 Free PMC article.

5

Colorectal tumourigenesis in carriers of the APC I1307K variant: lone gunman or conspiracy?

Sieber O, Lipton L, Heinimann K, Tomlinson I. Sieber O, et al. J Pathol. 2003 Feb;199(2):137-9. doi: 10.1002/path.1272. J Pathol. 2003. PMID: 12533824 Review.

6

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

Sieber OM, Lipton L, Crabtree M, Heinimann K, Fidalgo P, Phillips RK, Bisgaard ML, Orntoft TF, Aaltonen LA, Hodgson SV, Thomas HJ, Tomlinson IP. Sieber OM, et al. Among authors: tomlinson ip. N Engl J Med. 2003 Feb 27;348(9):791-9. doi: 10.1056/NEJMoa025283. N Engl J Med. 2003. PMID: 12606733 Free article.

7

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Halford SE, et al. Among authors: tomlinson ip. Am J Pathol. 2003 May;162(5):1545-8. doi: 10.1016/S0002-9440(10)64288-5. Am J Pathol. 2003. PMID: 12707038 Free PMC article.

8

Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.

Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP. Crabtree M, et al. Among authors: tomlinson ip. Oncogene. 2003 Jul 3;22(27):4257-65. doi: 10.1038/sj.onc.1206471. Oncogene. 2003. PMID: 12833148

9

Genomic instability--the engine of tumorigenesis?

Sieber OM, Heinimann K, Tomlinson IP. Sieber OM, et al. Among authors: tomlinson ip. Nat Rev Cancer. 2003 Sep;3(9):701-8. doi: 10.1038/nrc1170. Nat Rev Cancer. 2003. PMID: 12951589 Review.

10

Contribution of the CHEK2 1100delC variant to risk of multiple colorectal adenoma and carcinoma.

Lipton L, Fleischmann C, Sieber OM, Thomas HJ, Hodgson SV, Tomlinson IP, Houlston RS. Lipton L, et al. Among authors: tomlinson ip. Cancer Lett. 2003 Oct 28;200(2):149-52. doi: 10.1016/s0304-3835(03)00391-4. Cancer Lett. 2003. PMID: 14568168

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

651 results

Search Page