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Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.
Beaudoin M, Goyette P, Boucher G, Lo KS, Rivas MA, Stevens C, Alikashani A, Ladouceur M, Ellinghaus D, Törkvist L, Goel G, Lagacé C, Annese V, Bitton A, Begun J, Brant SR, Bresso F, Cho JH, Duerr RH, Halfvarson J, McGovern DP, Radford-Smith G, Schreiber S, Schumm PL, Sharma Y, Silverberg MS, Weersma RK; Quebec IBD Genetics Consortium; NIDDK IBD Genetics Consortium; International IBD Genetics Consortium; D'Amato M, Vermeire S, Franke A, Lettre G, Xavier RJ, Daly MJ, Rioux JD. Beaudoin M, et al. Among authors: begun j. PLoS Genet. 2013;9(9):e1003723. doi: 10.1371/journal.pgen.1003723. Epub 2013 Sep 12. PLoS Genet. 2013. PMID: 24068945 Free PMC article.
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.
Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ. Begun J, et al. Cell Rep. 2015 Jun 30;11(12):1905-18. doi: 10.1016/j.celrep.2015.05.045. Epub 2015 Jun 18. Cell Rep. 2015. PMID: 26095365 Free PMC article.
An Extremes of Phenotype Approach Confirms Significant Genetic Heterogeneity in Patients with Ulcerative Colitis.
Mortlock S, Lord A, Montgomery G, Zakrzewski M, Simms LA, Krishnaprasad K, Hanigan K, Doecke JD, Walsh A, Lawrance IC, Bampton PA, Andrews JM, Mahy G, Connor SJ, Sparrow MP, Bell S, Florin TH, Begun J, Gearry RB, Radford-Smith GL. Mortlock S, et al. Among authors: begun j. J Crohns Colitis. 2023 Mar 18;17(2):277-288. doi: 10.1093/ecco-jcc/jjac121. J Crohns Colitis. 2023. PMID: 36111848 Free PMC article.
Multinational evaluation of clinical decision-making in the treatment and management of mild-to-moderate ulcerative colitis.
Dignass AU, Paridaens K, Al Awadhi S, Begun J, Cheon JH, Fullarton JR, Louis E, Magro F, Marquez JR, Moschen AR, Narula N, Rydzewska G, Travis SPL. Dignass AU, et al. Among authors: begun j. Scand J Gastroenterol. 2022 Apr;57(4):424-431. doi: 10.1080/00365521.2021.2015801. Epub 2021 Dec 21. Scand J Gastroenterol. 2022. PMID: 34932423 Free article.
Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford.
Pulusu SSR, Srinivasan A, Krishnaprasad K, Cheng D, Begun J, Keung C, Van Langenberg D, Thin L, Mogilevski T, De Cruz P, Radford-Smith G, Flanagan E, Bell S, Kashkooli S, Sparrow M, Ghaly S, Bampton P, Sawyer E, Connor S, Rizvi QU, Andrews JM, Mahy G, Chivers P, Travis S, Lawrance IC. Pulusu SSR, et al. Among authors: begun j. World J Gastroenterol. 2020 Aug 14;26(30):4428-4441. doi: 10.3748/wjg.v26.i30.4428. World J Gastroenterol. 2020. PMID: 32874055 Free PMC article.
189 results