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HIF proteins connect the RB-E2F factors to angiogenesis.
Bakker WJ, Weijts BG, Westendorp B, de Bruin A. Bakker WJ, et al. Among authors: de bruin a. Transcription. 2013 Mar-Apr;4(2):62-6. doi: 10.4161/trns.23680. Epub 2013 Feb 14. Transcription. 2013. PMID: 23412359 Free PMC article.
Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.
Magliozzi R, Low TY, Weijts BG, Cheng T, Spanjaard E, Mohammed S, van Veen A, Ovaa H, de Rooij J, Zwartkruis FJ, Bos JL, de Bruin A, Heck AJ, Guardavaccaro D. Magliozzi R, et al. Among authors: de rooij j, de bruin a. Dev Cell. 2013 Dec 9;27(5):574-85. doi: 10.1016/j.devcel.2013.10.023. Epub 2013 Nov 27. Dev Cell. 2013. PMID: 24290981 Free article.
Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.
de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ. de Bruin A, et al. Among authors: a cornelissen pw. Nucleic Acids Res. 2016 May 5;44(8):3549-66. doi: 10.1093/nar/gkv1471. Epub 2015 Dec 17. Nucleic Acids Res. 2016. PMID: 26681691 Free PMC article.
Atypical E2Fs inhibit tumor angiogenesis.
Weijts BGMW, Westendorp B, Hien BT, Martínez-López LM, Zijp M, Thurlings I, Thomas RE, Schulte-Merker S, Bakker WJ, de Bruin A. Weijts BGMW, et al. Among authors: de bruin a. Oncogene. 2018 Jan 11;37(2):271-276. doi: 10.1038/onc.2017.336. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925392 Free PMC article.
Atypical E2f functions are critical for pancreas polyploidization.
Matondo RB, Moreno E, Toussaint MJM, Tooten PCJ, van Essen SC, van Liere EA, Youssef SA, Bongiovanni L, de Bruin A. Matondo RB, et al. Among authors: de bruin a. PLoS One. 2018 Jan 12;13(1):e0190899. doi: 10.1371/journal.pone.0190899. eCollection 2018. PLoS One. 2018. PMID: 29329320 Free PMC article.
381 results