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Altered histone acetylation is associated with age-dependent memory impairment in mice.
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. Peleg S, et al. Among authors: fischer a. Science. 2010 May 7;328(5979):753-6. doi: 10.1126/science.1186088. Science. 2010. PMID: 20448184
A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories.
Agis-Balboa RC, Arcos-Diaz D, Wittnam J, Govindarajan N, Blom K, Burkhardt S, Haladyniak U, Agbemenyah HY, Zovoilis A, Salinas-Riester G, Opitz L, Sananbenesi F, Fischer A. Agis-Balboa RC, et al. Among authors: fischer a. EMBO J. 2011 Aug 26;30(19):4071-83. doi: 10.1038/emboj.2011.293. EMBO J. 2011. PMID: 21873981 Free PMC article.
microRNA-34c is a novel target to treat dementias.
Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F, Fischer A. Zovoilis A, et al. Among authors: fischer a. EMBO J. 2011 Sep 23;30(20):4299-308. doi: 10.1038/emboj.2011.327. EMBO J. 2011. PMID: 21946562 Free PMC article.
HDAC1 regulates fear extinction in mice.
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F. Bahari-Javan S, et al. Among authors: fischer a. J Neurosci. 2012 Apr 11;32(15):5062-73. doi: 10.1523/JNEUROSCI.0079-12.2012. J Neurosci. 2012. PMID: 22496552 Free PMC article.
Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.
Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: fischer a. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.
5,158 results