Tuttle LM - Search Results

1

Divergent evolution of protein conformational dynamics in dihydrofolate reductase.

Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE. Bhabha G, et al. Among authors: tuttle lm. Nat Struct Mol Biol. 2013 Nov;20(11):1243-9. doi: 10.1038/nsmb.2676. Epub 2013 Sep 29. Nat Struct Mol Biol. 2013. PMID: 24077226 Free PMC article.

2

Side-chain conformational heterogeneity of intermediates in the Escherichia coli dihydrofolate reductase catalytic cycle.

Tuttle LM, Dyson HJ, Wright PE. Tuttle LM, et al. Biochemistry. 2013 May 21;52(20):3464-77. doi: 10.1021/bi400322e. Epub 2013 May 7. Biochemistry. 2013. PMID: 23614825 Free PMC article.

3

Side chain conformational averaging in human dihydrofolate reductase.

Tuttle LM, Dyson HJ, Wright PE. Tuttle LM, et al. Biochemistry. 2014 Feb 25;53(7):1134-45. doi: 10.1021/bi4015314. Epub 2014 Feb 13. Biochemistry. 2014. PMID: 24498949 Free PMC article.

4

Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR.

Bhabha G, Tuttle L, Martinez-Yamout MA, Wright PE. Bhabha G, et al. FEBS Lett. 2011 Nov 16;585(22):3528-32. doi: 10.1016/j.febslet.2011.10.014. Epub 2011 Oct 20. FEBS Lett. 2011. PMID: 22024482 Free PMC article.

5

BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.

Witus SR, Tuttle LM, Li W, Zelter A, Wang M, Kermoade KE, Wilburn DB, Davis TN, Brzovic PS, Zhao W, Klevit RE. Witus SR, et al. Among authors: tuttle lm. EMBO J. 2023 Aug 1;42(15):e113565. doi: 10.15252/embj.2023113565. Epub 2023 Jun 12. EMBO J. 2023. PMID: 37305927 Free article.

6

Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4.

Tuttle LM, Pacheco D, Warfield L, Wilburn DB, Hahn S, Klevit RE. Tuttle LM, et al. Nat Commun. 2021 Apr 13;12(1):2220. doi: 10.1038/s41467-021-22441-4. Nat Commun. 2021. PMID: 33850123 Free PMC article.

7

BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.

Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE. Witus SR, et al. Among authors: tuttle lm. Nat Struct Mol Biol. 2021 Mar;28(3):268-277. doi: 10.1038/s41594-020-00556-4. Epub 2021 Feb 15. Nat Struct Mol Biol. 2021. PMID: 33589814 Free PMC article.

8

Indirect sexual selection drives rapid sperm protein evolution in abalone.

Wilburn DB, Tuttle LM, Klevit RE, Swanson WJ. Wilburn DB, et al. Among authors: tuttle lm. Elife. 2019 Dec 23;8:e52628. doi: 10.7554/eLife.52628. Elife. 2019. PMID: 31868593 Free PMC article.

9

Large expert-curated database for benchmarking document similarity detection in biomedical literature search.

Brown P; RELISH Consortium; Zhou Y. Brown P, et al. Database (Oxford). 2019 Jan 1;2019:baz085. doi: 10.1093/database/baz085. Database (Oxford). 2019. PMID: 33326193 Free PMC article.

10

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.

Tuttle LM, Pacheco D, Warfield L, Luo J, Ranish J, Hahn S, Klevit RE. Tuttle LM, et al. Cell Rep. 2018 Mar 20;22(12):3251-3264. doi: 10.1016/j.celrep.2018.02.097. Cell Rep. 2018. PMID: 29562181 Free PMC article.

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