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Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2).
Perspicace E, Jouan-Hureaux V, Ragno R, Ballante F, Sartini S, La Motta C, Da Settimo F, Chen B, Kirsch G, Schneider S, Faivre B, Hesse S. Perspicace E, et al. Among authors: kirsch g. Eur J Med Chem. 2013 May;63:765-81. doi: 10.1016/j.ejmech.2013.03.022. Epub 2013 Mar 19. Eur J Med Chem. 2013. PMID: 23583911
Synthesis and bioactivity of novel amino-pyrazolopyridines.
Orlikova B, Chaouni W, Schumacher M, Aadil M, Diederich M, Kirsch G. Orlikova B, et al. Among authors: kirsch g. Eur J Med Chem. 2014 Oct 6;85:450-7. doi: 10.1016/j.ejmech.2014.08.008. Epub 2014 Aug 5. Eur J Med Chem. 2014. PMID: 25108361
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.
Zwergel C, Czepukojc B, Evain-Bana E, Xu Z, Stazi G, Mori M, Patsilinakos A, Mai A, Botta B, Ragno R, Bagrel D, Kirsch G, Meiser P, Jacob C, Montenarh M, Valente S. Zwergel C, et al. Among authors: kirsch g. Eur J Med Chem. 2017 Jul 7;134:316-333. doi: 10.1016/j.ejmech.2017.04.012. Epub 2017 Apr 10. Eur J Med Chem. 2017. PMID: 28431339
Screening of new antioxidant molecules using flow cytometry.
Ostrovidov S, Franck P, Joseph D, Martarello L, Kirsch G, Belleville F, Nabet P, Dousset B. Ostrovidov S, et al. Among authors: kirsch g. J Med Chem. 2000 May 4;43(9):1762-9. doi: 10.1021/jm991019j. J Med Chem. 2000. PMID: 10794693
194 results