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Overexpressing TNF-alpha in pancreatic ductal adenocarcinoma cells and fibroblasts modifies cell survival and reduces fatty acid synthesis via downregulation of sterol regulatory element binding protein-1 and activation of acetyl CoA carboxylase.
Al-Zoubi M, Chipitsyna G, Saxena S, Sarosiek K, Gandhi A, Kang CY, Relles D, Andrelsendecki J, Hyslop T, Yeo CJ, Arafat HA. Al-Zoubi M, et al. Among authors: arafat ha. J Gastrointest Surg. 2014 Feb;18(2):257-68; discussion 268. doi: 10.1007/s11605-013-2370-7. Epub 2013 Oct 4. J Gastrointest Surg. 2014. PMID: 24091913
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