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Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Mayer N, Schweiger M, Romauch M, Grabner GF, Eichmann TO, Fuchs E, Ivkovic J, Heier C, Mrak I, Lass A, Höfler G, Fledelius C, Zechner R, Zimmermann R, Breinbauer R. Mayer N, et al. Nat Chem Biol. 2013 Dec;9(12):785-7. doi: 10.1038/nchembio.1359. Epub 2013 Oct 6. Nat Chem Biol. 2013. PMID: 24096302 Free PMC article.
Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Schweiger M, Romauch M, Schreiber R, Grabner GF, Hütter S, Kotzbeck P, Benedikt P, Eichmann TO, Yamada S, Knittelfelder O, Diwoky C, Doler C, Mayer N, De Cecco W, Breinbauer R, Zimmermann R, Zechner R. Schweiger M, et al. Among authors: mayer n. Nat Commun. 2017 Mar 22;8:14859. doi: 10.1038/ncomms14859. Nat Commun. 2017. PMID: 28327588 Free PMC article.
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
Grabner GF, Guttenberger N, Mayer N, Migglautsch-Sulzer AK, Lembacher-Fadum C, Fawzy N, Bulfon D, Hofer P, Züllig T, Hartig L, Kulminskaya N, Chalhoub G, Schratter M, Radner FPW, Preiss-Landl K, Masser S, Lass A, Zechner R, Gruber K, Oberer M, Breinbauer R, Zimmermann R. Grabner GF, et al. Among authors: mayer n. J Am Chem Soc. 2022 Apr 13;144(14):6237-6250. doi: 10.1021/jacs.1c10836. Epub 2022 Apr 1. J Am Chem Soc. 2022. PMID: 35362954 Free PMC article.
Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.
Hofer P, Boeszoermenyi A, Jaeger D, Feiler U, Arthanari H, Mayer N, Zehender F, Rechberger G, Oberer M, Zimmermann R, Lass A, Haemmerle G, Breinbauer R, Zechner R, Preiss-Landl K. Hofer P, et al. Among authors: mayer n. J Biol Chem. 2015 Jul 24;290(30):18438-53. doi: 10.1074/jbc.M114.628958. Epub 2015 May 7. J Biol Chem. 2015. PMID: 25953897 Free PMC article.
Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Schweiger M, Romauch M, Schreiber R, Grabner GF, Hütter S, Kotzbeck P, Benedikt P, Eichmann TO, Yamada S, Knittelfelder O, Diwoky C, Doler C, Mayer N, De Cecco W, Breinbauer R, Zimmermann R, Zechner R. Schweiger M, et al. Among authors: mayer n. Nat Commun. 2017 Apr 25;8:15490. doi: 10.1038/ncomms15490. Nat Commun. 2017. PMID: 28440272 Free PMC article. No abstract available.
Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase.
Rengachari S, Aschauer P, Schittmayer M, Mayer N, Gruber K, Breinbauer R, Birner-Gruenberger R, Dreveny I, Oberer M. Rengachari S, et al. Among authors: mayer n. J Biol Chem. 2013 Oct 25;288(43):31093-104. doi: 10.1074/jbc.M113.491415. Epub 2013 Sep 6. J Biol Chem. 2013. PMID: 24014019 Free PMC article.
Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Aschauer P, Rengachari S, Lichtenegger J, Schittmayer M, Das KM, Mayer N, Breinbauer R, Birner-Gruenberger R, Gruber CC, Zimmermann R, Gruber K, Oberer M. Aschauer P, et al. Among authors: mayer n. Biochim Biophys Acta. 2016 May;1861(5):462-70. doi: 10.1016/j.bbalip.2016.02.005. Epub 2016 Feb 9. Biochim Biophys Acta. 2016. PMID: 26869448 Free article.
315 results