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Systems biology approaches to disease marker discovery.
Sharon D, Chen R, Snyder M. Sharon D, et al. Among authors: chen r. Dis Markers. 2010;28(4):209-24. doi: 10.3233/DMA-2010-0707. Dis Markers. 2010. PMID: 20534906 Free PMC article. Review.
Yeast proteomics and protein microarrays.
Chen R, Snyder M. Chen R, et al. J Proteomics. 2010 Oct 10;73(11):2147-57. doi: 10.1016/j.jprot.2010.08.003. Epub 2010 Aug 20. J Proteomics. 2010. PMID: 20728591 Free PMC article. Review.
Performance comparison of exome DNA sequencing technologies.
Clark MJ, Chen R, Lam HY, Karczewski KJ, Chen R, Euskirchen G, Butte AJ, Snyder M. Clark MJ, et al. Among authors: chen r. Nat Biotechnol. 2011 Sep 25;29(10):908-14. doi: 10.1038/nbt.1975. Nat Biotechnol. 2011. PMID: 21947028 Free PMC article.
The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome.
Paik YK, Jeong SK, Omenn GS, Uhlen M, Hanash S, Cho SY, Lee HJ, Na K, Choi EY, Yan F, Zhang F, Zhang Y, Snyder M, Cheng Y, Chen R, Marko-Varga G, Deutsch EW, Kim H, Kwon JY, Aebersold R, Bairoch A, Taylor AD, Kim KY, Lee EY, Hochstrasser D, Legrain P, Hancock WS. Paik YK, et al. Among authors: chen r. Nat Biotechnol. 2012 Mar 7;30(3):221-3. doi: 10.1038/nbt.2152. Nat Biotechnol. 2012. PMID: 22398612 No abstract available.
Systems biology: personalized medicine for the future?
Chen R, Snyder M. Chen R, et al. Curr Opin Pharmacol. 2012 Oct;12(5):623-8. doi: 10.1016/j.coph.2012.07.011. Epub 2012 Jul 31. Curr Opin Pharmacol. 2012. PMID: 22858243 Free PMC article. Review.
Promise of personalized omics to precision medicine.
Chen R, Snyder M. Chen R, et al. Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):73-82. doi: 10.1002/wsbm.1198. Epub 2012 Nov 26. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 23184638 Free PMC article. Review.
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.
Liu S, Im H, Bairoch A, Cristofanilli M, Chen R, Deutsch EW, Dalton S, Fenyo D, Fanayan S, Gates C, Gaudet P, Hincapie M, Hanash S, Kim H, Jeong SK, Lundberg E, Mias G, Menon R, Mu Z, Nice E, Paik YK, Uhlen M, Wells L, Wu SL, Yan F, Zhang F, Zhang Y, Snyder M, Omenn GS, Beavis RC, Hancock WS. Liu S, et al. Among authors: chen r. J Proteome Res. 2013 Jan 4;12(1):45-57. doi: 10.1021/pr300985j. Epub 2012 Dec 21. J Proteome Res. 2013. PMID: 23259914 Free PMC article.
Exome sequencing by targeted enrichment.
Clark MJ, Chen R, Snyder M. Clark MJ, et al. Among authors: chen r. Curr Protoc Mol Biol. 2013;Chapter 7:Unit7.12. doi: 10.1002/0471142727.mb0712s102. Curr Protoc Mol Biol. 2013. PMID: 23547016
Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias.
Chen R, Giliani S, Lanzi G, Mias GI, Lonardi S, Dobbs K, Manis J, Im H, Gallagher JE, Phanstiel DH, Euskirchen G, Lacroute P, Bettinger K, Moratto D, Weinacht K, Montin D, Gallo E, Mangili G, Porta F, Notarangelo LD, Pedretti S, Al-Herz W, Alfahdli W, Comeau AM, Traister RS, Pai SY, Carella G, Facchetti F, Nadeau KC, Snyder M, Notarangelo LD. Chen R, et al. J Allergy Clin Immunol. 2013 Sep;132(3):656-664.e17. doi: 10.1016/j.jaci.2013.06.013. Epub 2013 Jul 4. J Allergy Clin Immunol. 2013. PMID: 23830146 Free PMC article.
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