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Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas.
Gerlinger M, Quezada SA, Peggs KS, Furness AJ, Fisher R, Marafioti T, Shende VH, McGranahan N, Rowan AJ, Hazell S, Hamm D, Robins HS, Pickering L, Gore M, Nicol DL, Larkin J, Swanton C. Gerlinger M, et al. Among authors: swanton c. J Pathol. 2013 Dec;231(4):424-32. doi: 10.1002/path.4284. J Pathol. 2013. PMID: 24122851 Free PMC article.
Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets.
Swanton C, Larkin JM, Gerlinger M, Eklund AC, Howell M, Stamp G, Downward J, Gore M, Futreal PA, Escudier B, Andre F, Albiges L, Beuselinck B, Oudard S, Hoffmann J, Gyorffy B, Torrance CJ, Boehme KA, Volkmer H, Toschi L, Nicke B, Beck M, Szallasi Z. Swanton C, et al. Genome Med. 2010 Aug 11;2(8):53. doi: 10.1186/gm174. Genome Med. 2010. PMID: 20701793 Free PMC article.
Chromosomal instability confers intrinsic multidrug resistance.
Lee AJ, Endesfelder D, Rowan AJ, Walther A, Birkbak NJ, Futreal PA, Downward J, Szallasi Z, Tomlinson IP, Howell M, Kschischo M, Swanton C. Lee AJ, et al. Among authors: swanton c. Cancer Res. 2011 Mar 1;71(5):1858-70. doi: 10.1158/0008-5472.CAN-10-3604. Cancer Res. 2011. PMID: 21363922 Free PMC article.
Systemic therapy for advanced renal cell carcinoma.
Larkin JM, Kipps EL, Powell CJ, Swanton C. Larkin JM, et al. Among authors: swanton c. Ther Adv Med Oncol. 2009 Jul;1(1):15-27. doi: 10.1177/1758834009338430. Ther Adv Med Oncol. 2009. PMID: 21789110 Free PMC article.
CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction.
Lee AJ, Roylance R, Sander J, Gorman P, Endesfelder D, Kschischo M, Jones NP, East P, Nicke B, Spassieva S, Obeid LM, Birkbak NJ, Szallasi Z, McKnight NC, Rowan AJ, Speirs V, Hanby AM, Downward J, Tooze SA, Swanton C. Lee AJ, et al. Among authors: swanton c. J Pathol. 2012 Feb;226(3):482-94. doi: 10.1002/path.2998. Epub 2011 Oct 19. J Pathol. 2012. PMID: 21953249
447 results