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O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.
Nandakumar S, Kannanganat S, Dobos KM, Lucas M, Spencer JS, Fang S, McDonald MA, Pohl J, Birkness K, Chamcha V, Ramirez MV, Plikaytis BB, Posey JE, Amara RR, Sable SB. Nandakumar S, et al. Among authors: spencer js. PLoS Pathog. 2013;9(10):e1003705. doi: 10.1371/journal.ppat.1003705. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130497 Free PMC article. Clinical Trial.
Proteomic approaches to antigen discovery.
Dobos KM, Spencer JS, Orme IM, Belisle JT. Dobos KM, et al. Among authors: spencer js. Methods Mol Med. 2004;94:3-17. doi: 10.1385/1-59259-679-7:3. Methods Mol Med. 2004. PMID: 14959819
Deciphering the proteomic profile of Mycobacterium leprae cell envelope.
Marques MA, Neves-Ferreira AG, da Silveira EK, Valente RH, Chapeaurouge A, Perales J, da Silva Bernardes R, Dobos KM, Spencer JS, Brennan PJ, Pessolani MC. Marques MA, et al. Among authors: spencer js. Proteomics. 2008 Jun;8(12):2477-91. doi: 10.1002/pmic.200700971. Proteomics. 2008. PMID: 18563741
The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.
Wheat WH, Dhouib R, Angala SK, Larrouy-Maumus G, Dobos K, Nigou J, Spencer JS, Jackson M. Wheat WH, et al. Among authors: spencer js. Tuberculosis (Edinb). 2015 Jul;95(4):476-89. doi: 10.1016/j.tube.2015.04.002. Epub 2015 May 14. Tuberculosis (Edinb). 2015. PMID: 26048627 Free PMC article.
Continued proteomic analysis of Mycobacterium leprae subcellular fractions.
Marques MA, Espinosa BJ, Xavier da Silveira EK, Pessolani MC, Chapeaurouge A, Perales J, Dobos KM, Belisle JT, Spencer JS, Brennan PJ. Marques MA, et al. Among authors: spencer js. Proteomics. 2004 Oct;4(10):2942-53. doi: 10.1002/pmic.200400945. Proteomics. 2004. PMID: 15378742
Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae.
Bobosha K, Tjon Kon Fat EM, van den Eeden SJ, Bekele Y, van der Ploeg-van Schip JJ, de Dood CJ, Dijkman K, Franken KL, Wilson L, Aseffa A, Spencer JS, Ottenhoff TH, Corstjens PL, Geluk A. Bobosha K, et al. Among authors: spencer js. PLoS Negl Trop Dis. 2014 May 8;8(5):e2845. doi: 10.1371/journal.pntd.0002845. eCollection 2014 May. PLoS Negl Trop Dis. 2014. PMID: 24810599 Free PMC article.
111 results