Langston JW - Search Results

1

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Sanders LH, Laganière J, Cooper O, Mak SK, Vu BJ, Huang YA, Paschon DE, Vangipuram M, Sundararajan R, Urnov FD, Langston JW, Gregory PD, Zhang HS, Greenamyre JT, Isacson O, Schüle B. Sanders LH, et al. Among authors: langston jw. Neurobiol Dis. 2014 Feb;62:381-6. doi: 10.1016/j.nbd.2013.10.013. Epub 2013 Oct 19. Neurobiol Dis. 2014. PMID: 24148854 Free PMC article.

2

Mitochondrial dysfunction in skin fibroblasts from a Parkinson's disease patient with an alpha-synuclein triplication.

Mak SK, Tewari D, Tetrud JW, Langston JW, Schüle B. Mak SK, et al. Among authors: langston jw. J Parkinsons Dis. 2011;1(2):175-83. doi: 10.3233/JPD-2011-11025. J Parkinsons Dis. 2011. PMID: 23934919

3

Can cellular models revolutionize drug discovery in Parkinson's disease?

Schüle B, Pera RA, Langston JW. Schüle B, et al. Among authors: langston jw. Biochim Biophys Acta. 2009 Nov;1792(11):1043-51. doi: 10.1016/j.bbadis.2009.08.014. Epub 2009 Sep 3. Biochim Biophys Acta. 2009. PMID: 19733239 Free article. Review.

4

LRRK2 p.Ile1371Val Mutation in a Case with Neuropathologically Confirmed Multi-System Atrophy.

Lee K, Nguyen KD, Sun C, Liu M, Zafar F, Saetern J, Flierl A, Tetrud JW, Langston JW, Dickson D, Schüle B. Lee K, et al. Among authors: langston jw. J Parkinsons Dis. 2018;8(1):93-100. doi: 10.3233/JPD-171237. J Parkinsons Dis. 2018. PMID: 29480226 Review.

5

Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage.

Mak SK, Huang YA, Iranmanesh S, Vangipuram M, Sundararajan R, Nguyen L, Langston JW, Schüle B. Mak SK, et al. Among authors: langston jw. Stem Cells Int. 2012;2012:140427. doi: 10.1155/2012/140427. Epub 2012 Apr 10. Stem Cells Int. 2012. PMID: 22567022 Free PMC article.

6

α-Synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits.

Hallett PJ, McLean JR, Kartunen A, Langston JW, Isacson O. Hallett PJ, et al. Among authors: langston jw. Neurobiol Dis. 2012 Aug;47(2):258-67. doi: 10.1016/j.nbd.2012.04.009. Epub 2012 Apr 19. Neurobiol Dis. 2012. PMID: 22549133 Free PMC article.

7

Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: a biological link between Gaucher disease and parkinsonism.

Manning-Boğ AB, Schüle B, Langston JW. Manning-Boğ AB, et al. Among authors: langston jw. Neurotoxicology. 2009 Nov;30(6):1127-32. doi: 10.1016/j.neuro.2009.06.009. Epub 2009 Jul 2. Neurotoxicology. 2009. PMID: 19576930

8

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B. Flierl A, et al. Among authors: langston jw. PLoS One. 2014 Nov 12;9(11):e112413. doi: 10.1371/journal.pone.0112413. eCollection 2014. PLoS One. 2014. PMID: 25390032 Free PMC article.

9

Multisystem Lewy body disease and the other parkinsonian disorders.

Langston JW, Schüle B, Rees L, Nichols RJ, Barlow C. Langston JW, et al. Nat Genet. 2015 Dec;47(12):1378-84. doi: 10.1038/ng.3454. Nat Genet. 2015. PMID: 26620112

10

Is PARKIN parkinsonism a cancer predisposition syndrome?

Schüle B, Byrne C, Rees L, Langston JW. Schüle B, et al. Among authors: langston jw. Neurol Genet. 2015 Oct 15;1(4):e31. doi: 10.1212/NXG.0000000000000031. eCollection 2015 Dec. Neurol Genet. 2015. PMID: 27066568 Free PMC article.

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