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miR-139-5p is a regulator of metastatic pathways in breast cancer.
Krishnan K, Steptoe AL, Martin HC, Pattabiraman DR, Nones K, Waddell N, Mariasegaram M, Simpson PT, Lakhani SR, Vlassov A, Grimmond SM, Cloonan N. Krishnan K, et al. Among authors: waddell n. RNA. 2013 Dec;19(12):1767-80. doi: 10.1261/rna.042143.113. Epub 2013 Oct 24. RNA. 2013. PMID: 24158791 Free PMC article.
MicroRNA-182-5p targets a network of genes involved in DNA repair.
Krishnan K, Steptoe AL, Martin HC, Wani S, Nones K, Waddell N, Mariasegaram M, Simpson PT, Lakhani SR, Gabrielli B, Vlassov A, Cloonan N, Grimmond SM. Krishnan K, et al. Among authors: waddell n. RNA. 2013 Feb;19(2):230-42. doi: 10.1261/rna.034926.112. Epub 2012 Dec 18. RNA. 2013. PMID: 23249749 Free PMC article.
Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.
Bessette DC, Tilch E, Seidens T, Quinn MC, Wiegmans AP, Shi W, Cocciardi S, McCart-Reed A, Saunus JM, Simpson PT, Grimmond SM, Lakhani SR, Khanna KK, Waddell N, Al-Ejeh F, Chenevix-Trench G. Bessette DC, et al. Among authors: waddell n. PLoS One. 2015 May 13;10(5):e0125232. doi: 10.1371/journal.pone.0125232. eCollection 2015. PLoS One. 2015. PMID: 25969993 Free PMC article.
HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer.
Da Silva L, Simpson PT, Smart CE, Cocciardi S, Waddell N, Lane A, Morrison BJ, Vargas AC, Healey S, Beesley J, Pakkiri P, Parry S, Kurniawan N, Reid L, Keith P, Faria P, Pereira E, Skalova A, Bilous M, Balleine RL, Do H, Dobrovic A, Fox S, Franco M, Reynolds B, Khanna KK, Cummings M, Chenevix-Trench G, Lakhani SR. Da Silva L, et al. Among authors: waddell n. Breast Cancer Res. 2010;12(4):R46. doi: 10.1186/bcr2603. Epub 2010 Jul 6. Breast Cancer Res. 2010. PMID: 20604919 Free PMC article.
MicroRNAs and their isomiRs function cooperatively to target common biological pathways.
Cloonan N, Wani S, Xu Q, Gu J, Lea K, Heater S, Barbacioru C, Steptoe AL, Martin HC, Nourbakhsh E, Krishnan K, Gardiner B, Wang X, Nones K, Steen JA, Matigian NA, Wood DL, Kassahn KS, Waddell N, Shepherd J, Lee C, Ichikawa J, McKernan K, Bramlett K, Kuersten S, Grimmond SM. Cloonan N, et al. Among authors: waddell n. Genome Biol. 2011 Dec 30;12(12):R126. doi: 10.1186/gb-2011-12-12-r126. Genome Biol. 2011. PMID: 22208850 Free PMC article.
Sequencing transcriptomes in toto.
Kassahn KS, Waddell N, Grimmond SM. Kassahn KS, et al. Among authors: waddell n. Integr Biol (Camb). 2011 May;3(5):522-8. doi: 10.1039/c0ib00062k. Epub 2011 Feb 4. Integr Biol (Camb). 2011. PMID: 21298135 Review.
Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.
Nones K, Waddell N, Song S, Patch AM, Miller D, Johns A, Wu J, Kassahn KS, Wood D, Bailey P, Fink L, Manning S, Christ AN, Nourse C, Kazakoff S, Taylor D, Leonard C, Chang DK, Jones MD, Thomas M, Watson C, Pinese M, Cowley M, Rooman I, Pajic M; APGI; Butturini G, Malpaga A, Corbo V, Crippa S, Falconi M, Zamboni G, Castelli P, Lawlor RT, Gill AJ, Scarpa A, Pearson JV, Biankin AV, Grimmond SM. Nones K, et al. Among authors: waddell n. Int J Cancer. 2014 Sep 1;135(5):1110-8. doi: 10.1002/ijc.28765. Epub 2014 May 9. Int J Cancer. 2014. PMID: 24500968 Free article.
261 results