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Microarray analysis of genes with impaired insulin regulation in the skeletal muscle of type 2 diabetic patients indicates the involvement of basic helix-loop-helix domain-containing, class B, 2 protein (BHLHB2).
Rome S, Meugnier E, Lecomte V, Berbe V, Besson J, Cerutti C, Pesenti S, Granjon A, Disse E, Clement K, Lefai E, Laville M, Vidal H. Rome S, et al. Among authors: pesenti s. Diabetologia. 2009 Sep;52(9):1899-912. doi: 10.1007/s00125-009-1442-4. Epub 2009 Jul 10. Diabetologia. 2009. PMID: 19590847
FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.
Bravard A, Lefai E, Meugnier E, Pesenti S, Disse E, Vouillarmet J, Peretti N, Rabasa-Lhoret R, Laville M, Vidal H, Rieusset J. Bravard A, et al. Among authors: pesenti s. Diabetes. 2011 Jan;60(1):258-68. doi: 10.2337/db10-0281. Epub 2010 Oct 13. Diabetes. 2011. PMID: 20943749 Free PMC article.
Grape polyphenols prevent fructose-induced oxidative stress and insulin resistance in first-degree relatives of type 2 diabetic patients.
Hokayem M, Blond E, Vidal H, Lambert K, Meugnier E, Feillet-Coudray C, Coudray C, Pesenti S, Luyton C, Lambert-Porcheron S, Sauvinet V, Fedou C, Brun JF, Rieusset J, Bisbal C, Sultan A, Mercier J, Goudable J, Dupuy AM, Cristol JP, Laville M, Avignon A. Hokayem M, et al. Among authors: pesenti s. Diabetes Care. 2013 Jun;36(6):1454-61. doi: 10.2337/dc12-1652. Epub 2012 Dec 28. Diabetes Care. 2013. PMID: 23275372 Free PMC article. Clinical Trial.
Retraction for Li et al., "ATAD3 Is a Limiting Factor in Mitochondrial Biogenesis and Adipogenesis of White Adipocyte-Like 3T3-L1 Cells".
Li S, Yao Y, Xu R, Pesenti S, Cottet-Rousselle C, Rieusset J, Tokarska-Schlattner M, Liao K, Schlattner U, Rousseau D. Li S, et al. Among authors: pesenti s. Mol Cell Biol. 2017 May 2;37(10):e01170-13. doi: 10.1128/MCB.01170-13. Print 2017 May 15. Mol Cell Biol. 2017. PMID: 24732801 Free PMC article. No abstract available.
Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice.
Aswad H, Forterre A, Wiklander OP, Vial G, Danty-Berger E, Jalabert A, Lamazière A, Meugnier E, Pesenti S, Ott C, Chikh K, El-Andaloussi S, Vidal H, Lefai E, Rieusset J, Rome S. Aswad H, et al. Among authors: pesenti s. Diabetologia. 2014 Oct;57(10):2155-64. doi: 10.1007/s00125-014-3337-2. Epub 2014 Jul 30. Diabetologia. 2014. PMID: 25073444 Free PMC article.
156 results