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Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC. Emerling BM, et al. Among authors: bell el. Cell. 2013 Nov 7;155(4):844-57. doi: 10.1016/j.cell.2013.09.057. Cell. 2013. PMID: 24209622 Free PMC article.
Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients.
Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H, Choo-Wing R, Bellinger G, Tsukazawa KS, Brown V, Signoretti S, Soltoff SP, Cantley LC. Emerling BM, et al. Among authors: bell el. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3483-8. doi: 10.1073/pnas.1222435110. Epub 2013 Feb 1. Proc Natl Acad Sci U S A. 2013. PMID: 23378636 Free PMC article.
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive.
Libert S, Pointer K, Bell EL, Das A, Cohen DE, Asara JM, Kapur K, Bergmann S, Preisig M, Otowa T, Kendler KS, Chen X, Hettema JM, van den Oord EJ, Rubio JP, Guarente L. Libert S, et al. Among authors: bell el. Cell. 2011 Dec 23;147(7):1459-72. doi: 10.1016/j.cell.2011.10.054. Epub 2011 Dec 8. Cell. 2011. PMID: 22169038 Free PMC article.
Mitochondrial regulation of oxygen sensing.
Bell EL, Emerling BM, Chandel NS. Bell EL, et al. Mitochondrion. 2005 Oct;5(5):322-32. doi: 10.1016/j.mito.2005.06.005. Mitochondrion. 2005. PMID: 16146708 Review.
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.
Fendt SM, Bell EL, Keibler MA, Davidson SM, Wirth GJ, Fiske B, Mayers JR, Schwab M, Bellinger G, Csibi A, Patnaik A, Blouin MJ, Cantley LC, Guarente L, Blenis J, Pollak MN, Olumi AF, Vander Heiden MG, Stephanopoulos G. Fendt SM, et al. Among authors: bell el. Cancer Res. 2013 Jul 15;73(14):4429-38. doi: 10.1158/0008-5472.CAN-13-0080. Epub 2013 May 17. Cancer Res. 2013. PMID: 23687346 Free PMC article.
42 results