Barford D - Search Results

1

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.

Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli JP, Hendricks A, Keogh JM, Henning E, Doree D, Jeter-Jones S, Garg S, Bochukova EG, Bounds R, Ashford S, Gayton E, Hindmarsh PC, Shield JP, Crowne E, Barford D, Wareham NJ; UK10K consortium; O'Rahilly S, Murphy MP, Powell DR, Barroso I, Farooqi IS. Pearce LR, et al. Among authors: barford d. Cell. 2013 Nov 7;155(4):765-77. doi: 10.1016/j.cell.2013.09.058. Cell. 2013. PMID: 24209692 Free PMC article.

2

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I. George S, et al. Among authors: barford d. Science. 2004 May 28;304(5675):1325-8. doi: 10.1126/science.1096706. Science. 2004. PMID: 15166380 Free PMC article.

3

Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.

Garnett MJ, Rana S, Paterson H, Barford D, Marais R. Garnett MJ, et al. Among authors: barford d. Mol Cell. 2005 Dec 22;20(6):963-9. doi: 10.1016/j.molcel.2005.10.022. Mol Cell. 2005. PMID: 16364920 Free article.

4

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.

Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R; Cancer Genome Project. Wan PT, et al. Among authors: barford d. Cell. 2004 Mar 19;116(6):855-67. doi: 10.1016/s0092-8674(04)00215-6. Cell. 2004. PMID: 15035987 Free article.

5

Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.

Haque A, Andersen JN, Salmeen A, Barford D, Tonks NK. Haque A, et al. Among authors: barford d. Cell. 2011 Sep 30;147(1):185-98. doi: 10.1016/j.cell.2011.08.036. Cell. 2011. PMID: 21962515 Free PMC article.

6

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

Yang J, Cron P, Thompson V, Good VM, Hess D, Hemmings BA, Barford D. Yang J, et al. Among authors: barford d. Mol Cell. 2002 Jun;9(6):1227-40. doi: 10.1016/s1097-2765(02)00550-6. Mol Cell. 2002. PMID: 12086620 Free article.

7

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.

Salmeen A, Andersen JN, Myers MP, Tonks NK, Barford D. Salmeen A, et al. Among authors: barford d. Mol Cell. 2000 Dec;6(6):1401-12. doi: 10.1016/s1097-2765(00)00137-4. Mol Cell. 2000. PMID: 11163213 Free article.

8

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.

Brennan DF, Dar AC, Hertz NT, Chao WC, Burlingame AL, Shokat KM, Barford D. Brennan DF, et al. Among authors: barford d. Nature. 2011 Apr 21;472(7343):366-9. doi: 10.1038/nature09860. Epub 2011 Mar 27. Nature. 2011. PMID: 21441910

9

Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.

Song H, Hanlon N, Brown NR, Noble ME, Johnson LN, Barford D. Song H, et al. Among authors: barford d. Mol Cell. 2001 Mar;7(3):615-26. doi: 10.1016/s1097-2765(01)00208-8. Mol Cell. 2001. PMID: 11463386 Free article.

10

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module.

Komander D, Lord CJ, Scheel H, Swift S, Hofmann K, Ashworth A, Barford D. Komander D, et al. Among authors: barford d. Mol Cell. 2008 Feb 29;29(4):451-64. doi: 10.1016/j.molcel.2007.12.018. Mol Cell. 2008. PMID: 18313383 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

178 results

Search Page