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Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, Adams RH, Sheppard D. Henderson NC, et al. Among authors: iredale jp. Nat Med. 2013 Dec;19(12):1617-24. doi: 10.1038/nm.3282. Epub 2013 Nov 10. Nat Med. 2013. PMID: 24216753 Free PMC article.
αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis.
Murray IR, Gonzalez ZN, Baily J, Dobie R, Wallace RJ, Mackinnon AC, Smith JR, Greenhalgh SN, Thompson AI, Conroy KP, Griggs DW, Ruminski PG, Gray GA, Singh M, Campbell MA, Kendall TJ, Dai J, Li Y, Iredale JP, Simpson H, Huard J, Péault B, Henderson NC. Murray IR, et al. Among authors: iredale jp. Nat Commun. 2017 Oct 24;8(1):1118. doi: 10.1038/s41467-017-01097-z. Nat Commun. 2017. PMID: 29061963 Free PMC article.
Modeling liver fibrosis in rodents.
Constandinou C, Henderson N, Iredale JP. Constandinou C, et al. Among authors: iredale jp. Methods Mol Med. 2005;117:237-50. doi: 10.1385/1-59259-940-0:237. Methods Mol Med. 2005. PMID: 16118456
Galectin-3 regulates myofibroblast activation and hepatic fibrosis.
Henderson NC, Mackinnon AC, Farnworth SL, Poirier F, Russo FP, Iredale JP, Haslett C, Simpson KJ, Sethi T. Henderson NC, et al. Among authors: iredale jp. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5060-5. doi: 10.1073/pnas.0511167103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549783 Free PMC article.
Reversibility of liver fibrosis.
Pellicoro A, Ramachandran P, Iredale JP. Pellicoro A, et al. Among authors: iredale jp. Fibrogenesis Tissue Repair. 2012 Jun 6;5(Suppl 1):S26. doi: 10.1186/1755-1536-5-S1-S26. eCollection 2012. Fibrogenesis Tissue Repair. 2012. PMID: 23259590 Free PMC article.
Reply to Elastin-based molecular MRI of liver fibrosis.
Pellicoro A, Iredale JP. Pellicoro A, et al. Among authors: iredale jp. Hepatology. 2013 Oct;58(4):1518-9. doi: 10.1002/hep.26332. Epub 2013 Sep 4. Hepatology. 2013. PMID: 23424101 No abstract available.
180 results