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RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.
Jiang Z, Jones R, Liu JC, Deng T, Robinson T, Chung PE, Wang S, Herschkowitz JI, Egan SE, Perou CM, Zacksenhaus E. Jiang Z, et al. Among authors: egan se. Cell Cycle. 2011 May 15;10(10):1563-70. doi: 10.4161/cc.10.10.15703. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21502814 Review.
Elevated PI3K signaling drives multiple breast cancer subtypes.
Adams JR, Schachter NF, Liu JC, Zacksenhaus E, Egan SE. Adams JR, et al. Among authors: egan se. Oncotarget. 2011 Jun;2(6):435-47. doi: 10.18632/oncotarget.285. Oncotarget. 2011. PMID: 21646685 Free PMC article. Review.
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE. Xu K, et al. Among authors: egan se. Cancer Cell. 2012 May 15;21(5):626-641. doi: 10.1016/j.ccr.2012.03.041. Cancer Cell. 2012. PMID: 22624713 Free PMC article.
Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast.
An Y, Adams JR, Hollern DP, Zhao A, Chang SG, Gams MS, Chung PED, He X, Jangra R, Shah JS, Yang J, Beck LA, Raghuram N, Kozma KJ, Loch AJ, Wang W, Fan C, Done SJ, Zacksenhaus E, Guidos CJ, Perou CM, Egan SE. An Y, et al. Among authors: egan se. Cell Rep. 2018 Oct 16;25(3):702-714.e6. doi: 10.1016/j.celrep.2018.09.056. Cell Rep. 2018. PMID: 30332649 Free PMC article.
Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Schachter NF, Adams JR, Skowron P, Kozma KJ, Lee CA, Raghuram N, Yang J, Loch AJ, Wang W, Kucharczuk A, Wright KL, Quintana RM, An Y, Dotzko D, Gorman JL, Wojtal D, Shah JS, Leon-Gomez P, Pellecchia G, Dupuy AJ, Perou CM, Ben-Porath I, Karni R, Zacksenhaus E, Woodgett JR, Done SJ, Garzia L, Sorana Morrissy A, Reimand J, Taylor MD, Egan SE. Schachter NF, et al. Among authors: egan se. Nat Commun. 2021 Sep 2;12(1):5238. doi: 10.1038/s41467-021-25467-w. Nat Commun. 2021. PMID: 34475389 Free PMC article.
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.
Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D. Langille E, et al. Among authors: egan se. Cancer Discov. 2022 Dec 2;12(12):2930-2953. doi: 10.1158/2159-8290.CD-21-0865. Cancer Discov. 2022. PMID: 36108220 Free PMC article.
95 results