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The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma.
Clin Cancer Res. 2014 Jan 15;20(2):469-79. doi: 10.1158/1078-0432.CCR-13-1302. Epub 2013 Nov 18.
Clin Cancer Res. 2014.
PMID: 24246358
Clinical Trial.
Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients.
Eren R, Landstein D, Terkieltaub D, Nussbaum O, Zauberman A, Ben-Porath J, Gopher J, Buchnick R, Kovjazin R, Rosenthal-Galili Z, Aviel S, Ilan E, Shoshany Y, Neville L, Waisman T, Ben-Moshe O, Kischitsky A, Foung SK, Keck ZY, Pappo O, Eid A, Jurim O, Zamir G, Galun E, Dagan S.
Eren R, et al. Among authors: aviel s.
J Virol. 2006 Mar;80(6):2654-64. doi: 10.1128/JVI.80.6.2654-2664.2006.
J Virol. 2006.
PMID: 16501075
Free PMC article.
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Adaptive alternative splicing correlates with less environmental risk of parkinsonism.
Benmoyal-Segal L, Soreq L, Ben-Shaul Y, Ben-Ari S, Ben-Moshe T, Aviel S, Bergman H, Soreq H.
Benmoyal-Segal L, et al. Among authors: aviel s.
Neurodegener Dis. 2012;9(2):87-98. doi: 10.1159/000331328. Epub 2011 Oct 27.
Neurodegener Dis. 2012.
PMID: 22042332
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Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue.
Aviel S, Winberg G, Massucci M, Ciechanover A.
Aviel S, et al.
J Biol Chem. 2000 Aug 4;275(31):23491-9. doi: 10.1074/jbc.M002052200.
J Biol Chem. 2000.
PMID: 10807912
Free article.
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Ig light chains are secreted predominantly as monomers.
Dul JL, Aviel S, Melnick J, Argon Y.
Dul JL, et al. Among authors: aviel s.
J Immunol. 1996 Oct 1;157(7):2969-75.
J Immunol. 1996.
PMID: 8816404
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Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants.
Hendershot L, Wei J, Gaut J, Melnick J, Aviel S, Argon Y.
Hendershot L, et al. Among authors: aviel s.
Proc Natl Acad Sci U S A. 1996 May 28;93(11):5269-74. doi: 10.1073/pnas.93.11.5269.
Proc Natl Acad Sci U S A. 1996.
PMID: 8643565
Free PMC article.
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Rapid degradation of an unassembled immunoglobulin light chain is mediated by a serine protease and occurs in a pre-Golgi compartment.
Gardner AM, Aviel S, Argon Y.
Gardner AM, et al. Among authors: aviel s.
J Biol Chem. 1993 Dec 5;268(34):25940-7.
J Biol Chem. 1993.
PMID: 8245027
Free article.
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The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains.
Melnick J, Aviel S, Argon Y.
Melnick J, et al. Among authors: aviel s.
J Biol Chem. 1992 Oct 25;267(30):21303-6.
J Biol Chem. 1992.
PMID: 1400441
Free article.
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