Auld DS - Search Results

1

Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.

Zhang JH, Kang ZB, Ardayfio O, Ho PI, Smith T, Wallace I, Bowes S, Hill WA, Auld DS. Zhang JH, et al. Among authors: auld ds. J Biomol Screen. 2014 Jun;19(5):651-60. doi: 10.1177/1087057113512151. Epub 2013 Nov 18. J Biomol Screen. 2014. PMID: 24246376

2

Monitoring compound integrity with cytochrome P450 assays and qHTS.

MacArthur R, Leister W, Veith H, Shinn P, Southall N, Austin CP, Inglese J, Auld DS. MacArthur R, et al. Among authors: auld ds. J Biomol Screen. 2009 Jun;14(5):538-46. doi: 10.1177/1087057109336954. Epub 2009 May 29. J Biomol Screen. 2009. PMID: 19483146 Free PMC article.

3

A sensitive, homogeneous, and high-throughput assay for lysine-specific histone demethylases at the H3K4 site.

Wang C, Caron M, Burdick D, Kang Z, Auld D, Hill WA, Padrós J, Zhang JH. Wang C, et al. Assay Drug Dev Technol. 2012 Apr;10(2):179-86. doi: 10.1089/adt.2011.0395. Epub 2011 Dec 22. Assay Drug Dev Technol. 2012. PMID: 22192306

4

Comparison of compound administration methods in biochemical assays: effects on apparent compound potency using either assay-ready compound plates or pin tool-delivered compounds.

Smith T, Ho PI, Yue K, Itkin Z, MacDougall D, Paolucci M, Hill A, Auld DS. Smith T, et al. Among authors: auld ds. J Biomol Screen. 2013 Jan;18(1):14-25. doi: 10.1177/1087057112455434. Epub 2012 Aug 17. J Biomol Screen. 2013. PMID: 22904199

5

Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.

Ho PI, Yue K, Pandey P, Breault L, Harbinski F, McBride AJ, Webb B, Narahari J, Karassina N, Wood KV, Hill A, Auld DS. Ho PI, et al. Among authors: auld ds. ACS Chem Biol. 2013 May 17;8(5):1009-17. doi: 10.1021/cb3007264. Epub 2013 Mar 26. ACS Chem Biol. 2013. PMID: 23485150

6

Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening.

Auld DS, Jimenez M, Yue K, Busby S, Chen YC, Bowes S, Wendel G, Smith T, Zhang JH. Auld DS, et al. J Biomol Screen. 2016 Dec;21(10):1075-1089. doi: 10.1177/1087057116667255. Epub 2016 Sep 27. J Biomol Screen. 2016. PMID: 27601436

7

Characterization and Use of TurboLuc Luciferase as a Reporter for High-Throughput Assays.

Auld DS, Narahari J, Ho PI, Casalena D, Nguyen V, Cirbaite E, Hughes D, Daly J, Webb B. Auld DS, et al. Biochemistry. 2018 Aug 7;57(31):4700-4706. doi: 10.1021/acs.biochem.8b00290. Epub 2018 Apr 20. Biochemistry. 2018. PMID: 29641191

8

A Scalable Pipeline for High-Throughput Flow Cytometry.

Wilson AC, Moutsatsos IK, Yu G, Pineda JJ, Feng Y, Auld DS. Wilson AC, et al. Among authors: auld ds. SLAS Discov. 2018 Aug;23(7):708-718. doi: 10.1177/2472555218774770. Epub 2018 May 16. SLAS Discov. 2018. PMID: 29768981 Free article.

9

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.

Griner LM, Gampa K, Do T, Nguyen H, Farley D, Hogan CJ, Auld DS, Silver SJ. Griner LM, et al. Among authors: auld ds. J Vis Exp. 2018 Sep 5;(139):57476. doi: 10.3791/57476. J Vis Exp. 2018. PMID: 30247463 Free PMC article.

10

Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening.

Okesli-Armlovich A, Gupta A, Jimenez M, Auld D, Liu Q, Bassik MC, Khosla C. Okesli-Armlovich A, et al. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2559-2564. doi: 10.1016/j.bmcl.2019.08.010. Epub 2019 Aug 7. Bioorg Med Chem Lett. 2019. PMID: 31420268 Free PMC article.

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