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Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, Aichinger MC, Napolitani G, Qi X, van der Merwe PA, Wojno J, Veerapen N, Cox LR, Besra GS, Yuan W, Cresswell P, Cerundolo V. Salio M, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4753-61. doi: 10.1073/pnas.1310050110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248359 Free PMC article.
Human autoreactive T cells recognize CD1b and phospholipids.
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB. Van Rhijn I, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):380-5. doi: 10.1073/pnas.1520947112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2016. PMID: 26621732 Free PMC article.
Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.
Salio M, Gasser O, Gonzalez-Lopez C, Martens A, Veerapen N, Gileadi U, Verter JG, Napolitani G, Anderson R, Painter G, Besra GS, Hermans IF, Cerundolo V. Salio M, et al. Among authors: napolitani g. J Immunol. 2017 Oct 15;199(8):2631-2638. doi: 10.4049/jimmunol.1700615. Epub 2017 Sep 6. J Immunol. 2017. PMID: 28877992 Free PMC article.
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ, Napolitani G, Shepherd D, Ghadbane H, Kurupati P, Preciado-Llanes L, Rei M, Dobinson HC, Gibani MM, Teng KWW, Newell EW, Veerapen N, Besra GS, Pollard AJ, Cerundolo V. Howson LJ, et al. Among authors: napolitani g. Nat Commun. 2018 Jan 17;9(1):253. doi: 10.1038/s41467-017-02540-x. Nat Commun. 2018. PMID: 29343684 Free PMC article.
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.
Preciado-Llanes L, Aulicino A, Canals R, Moynihan PJ, Zhu X, Jambo N, Nyirenda TS, Kadwala I, Sousa Gerós A, Owen SV, Jambo KC, Kumwenda B, Veerapen N, Besra GS, Gordon MA, Hinton JCD, Napolitani G, Salio M, Simmons A. Preciado-Llanes L, et al. Among authors: napolitani g. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20717-20728. doi: 10.1073/pnas.2007472117. Epub 2020 Aug 11. Proc Natl Acad Sci U S A. 2020. PMID: 32788367 Free PMC article.
Intestinal DC in migrational imprinting of immune cells.
Stock A, Napolitani G, Cerundolo V. Stock A, et al. Among authors: napolitani g. Immunol Cell Biol. 2013 Mar;91(3):240-9. doi: 10.1038/icb.2012.73. Epub 2013 Jan 8. Immunol Cell Biol. 2013. PMID: 23295361 Review.
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.
Crump NT, Hadjinicolaou AV, Xia M, Walsby-Tickle J, Gileadi U, Chen JL, Setshedi M, Olsen LR, Lau IJ, Godfrey L, Quek L, Yu Z, Ballabio E, Barnkob MB, Napolitani G, Salio M, Koohy H, Kessler BM, Taylor S, Vyas P, McCullagh JSO, Milne TA, Cerundolo V. Crump NT, et al. Among authors: napolitani g. Cell Rep. 2021 May 11;35(6):109101. doi: 10.1016/j.celrep.2021.109101. Cell Rep. 2021. PMID: 33979616 Free PMC article.
42 results