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Early-life adversity selectively impairs α2-GABAA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine.
Mitchell SJ, Maguire EP, Cunningham L, Gunn BG, Linke M, Zechner U, Dixon CI, King SL, Stephens DN, Swinny JD, Belelli D, Lambert JJ. Mitchell SJ, et al. Among authors: maguire ep. Neuropharmacology. 2018 Oct;141:98-112. doi: 10.1016/j.neuropharm.2018.08.021. Epub 2018 Aug 21. Neuropharmacology. 2018. PMID: 30138693 Free PMC article.
Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition.
Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, Robinson I, Guerrini I, McQuillin A, Fisher EM, Ungless MA, Gurling HM, Morgan MY, Brown SD, Stephens DN, Belelli D, Lambert JJ, Smart TG, Thomas HC. Anstee QM, et al. Among authors: maguire ep. Nat Commun. 2013;4:2816. doi: 10.1038/ncomms3816. Nat Commun. 2013. PMID: 24281383 Free PMC article.