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Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS. Aerts JM, et al. Among authors: van eijk m. Diabetes. 2007 May;56(5):1341-9. doi: 10.2337/db06-1619. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287460 Free PMC article.
Glycosphingolipids and insulin resistance.
Aerts JM, Boot RG, van Eijk M, Groener J, Bijl N, Lombardo E, Bietrix FM, Dekker N, Groen AK, Ottenhoff R, van Roomen C, Aten J, Serlie M, Langeveld M, Wennekes T, Overkleeft HS. Aerts JM, et al. Among authors: van eijk m, van roomen c. Adv Exp Med Biol. 2011;721:99-119. doi: 10.1007/978-1-4614-0650-1_7. Adv Exp Med Biol. 2011. PMID: 21910085 Review.
The Unique Phenotype of Lipid-Laden Macrophages.
van Eijk M, Aerts JMFG. van Eijk M, et al. Int J Mol Sci. 2021 Apr 14;22(8):4039. doi: 10.3390/ijms22084039. Int J Mol Sci. 2021. PMID: 33919858 Free PMC article. Review.
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
Herrera Moro Chao D, Wang Y, Foppen E, Ottenhoff R, van Roomen C, Parlevliet ET, van Eijk M, Verhoek M, Boot R, Marques AR, Scheij S, Mirzaian M, Kooijman S, Jansen K, Wang D, Mergen C, Seeley RJ, Tschöp MH, Overkleeft H, Rensen PCN, Kalsbeek A, Aerts JMFG, Yi CX. Herrera Moro Chao D, et al. Among authors: van eijk m, van roomen c. Diabetes. 2019 Dec;68(12):2223-2234. doi: 10.2337/db19-0049. Epub 2019 Oct 2. Diabetes. 2019. PMID: 31578192
HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.
Tol MJ, van der Lienden MJC, Gabriel TL, Hagen JJ, Scheij S, Veenendaal T, Klumperman J, Donker-Koopman WE, Verhoeven AJ, Overkleeft H, Aerts JM, Argmann CA, van Eijk M. Tol MJ, et al. Among authors: van eijk m, van der lienden mjc. Autophagy. 2018;14(3):437-449. doi: 10.1080/15548627.2017.1419118. Epub 2018 Feb 17. Autophagy. 2018. PMID: 29455584 Free PMC article.
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
van Eijk M, Aten J, Bijl N, Ottenhoff R, van Roomen CP, Dubbelhuis PF, Seeman I, Ghauharali-van der Vlugt K, Overkleeft HS, Arbeeny C, Groen AK, Aerts JM. van Eijk M, et al. Among authors: van roomen cp. PLoS One. 2009;4(3):e4723. doi: 10.1371/journal.pone.0004723. Epub 2009 Mar 23. PLoS One. 2009. PMID: 19305508 Free PMC article.
217 results