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Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis.
Zhang J, Sandroni PB, Huang W, Gao X, Oswalt L, Schroder MA, Lee S, Shih YI, Huang HS, Swigart PM, Myagmar BE, Simpson PC, Rossi JS, Schisler JC, Jensen BC. Zhang J, et al. Among authors: simpson pc. JACC Basic Transl Sci. 2023 Nov 15;9(1):78-96. doi: 10.1016/j.jacbts.2023.08.013. eCollection 2024 Jan. JACC Basic Transl Sci. 2023. PMID: 38362342 Free PMC article.
The alpha-1A adrenergic receptor regulates mitochondrial oxidative metabolism in the mouse heart.
Sandroni PB, Schroder MA, Hawkins HT, Bailon JD, Huang W, Hagen JT, Montgomery M, Hong SJ, Chin AL, Zhang J, Rodrigo MC, Kim B, Simpson PC, Schisler JC, Ellis JM, Fisher-Wellman KH, Jensen BC. Sandroni PB, et al. Among authors: simpson pc. J Mol Cell Cardiol. 2024 Feb;187:101-117. doi: 10.1016/j.yjmcc.2023.12.003. Epub 2024 Feb 6. J Mol Cell Cardiol. 2024. PMID: 38331556
Norepinephrine links astrocytic activity to regulation of cortical state.
Reitman ME, Tse V, Mi X, Willoughby DD, Peinado A, Aivazidis A, Myagmar BE, Simpson PC, Bayraktar OA, Yu G, Poskanzer KE. Reitman ME, et al. Among authors: simpson pc. Nat Neurosci. 2023 Apr;26(4):579-593. doi: 10.1038/s41593-023-01284-w. Epub 2023 Mar 30. Nat Neurosci. 2023. PMID: 36997759 Free PMC article.
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy.
Rupert C, López JE, Cortez-Toledo E, De la Cruz Cabrera O, Chesler NC, Simpson PC, Campbell SG, Baker AJ. Rupert C, et al. Among authors: simpson pc. Am J Physiol Heart Circ Physiol. 2023 Mar 1;324(3):H293-H304. doi: 10.1152/ajpheart.00279.2022. Epub 2023 Jan 13. Am J Physiol Heart Circ Physiol. 2023. PMID: 36637971 Free PMC article.
Reversal of right ventricular failure by chronic α1A-subtype adrenergic agonist therapy.
Cowley PM, Wang G, Swigart PM, Raghunathan A, Reddy N, Dulam P, Lovett DH, Simpson PC, Baker AJ. Cowley PM, et al. Among authors: simpson pc. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H224-H232. doi: 10.1152/ajpheart.00507.2018. Epub 2018 Nov 9. Am J Physiol Heart Circ Physiol. 2019. PMID: 30412439 Free PMC article.
114 results