Ahmed R - Search Results

1

Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG, Kaufmann DE. Porichis F, et al. Among authors: ahmed r. J Virol. 2014 Mar;88(5):2508-18. doi: 10.1128/JVI.02034-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352453 Free PMC article.

2

Restoring function in exhausted CD8 T cells during chronic viral infection.

Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R. Barber DL, et al. Among authors: ahmed r. Nature. 2006 Feb 9;439(7077):682-7. doi: 10.1038/nature04444. Epub 2005 Dec 28. Nature. 2006. PMID: 16382236

3

HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.

Wherry EJ, Day CL, Draenert R, Miller JD, Kiepiela P, Woodberry T, Brander C, Addo M, Klenerman P, Ahmed R, Walker BD. Wherry EJ, et al. Among authors: ahmed r. Virology. 2006 Sep 30;353(2):366-73. doi: 10.1016/j.virol.2006.06.017. Epub 2006 Jul 24. Virology. 2006. PMID: 16860834 Free PMC article.

4

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.

Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: ahmed r. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384

5

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.

Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Freeman GJ, et al. Among authors: ahmed r. J Exp Med. 2006 Oct 2;203(10):2223-7. doi: 10.1084/jem.20061800. Epub 2006 Sep 25. J Exp Med. 2006. PMID: 17000870 Free PMC article. Review.

6

Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.

Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: ahmed r. J Virol. 2007 Mar;81(6):2545-53. doi: 10.1128/JVI.02021-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182670 Free PMC article.

7

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection.

Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. Sharpe AH, et al. Among authors: ahmed r. Nat Immunol. 2007 Mar;8(3):239-45. doi: 10.1038/ni1443. Nat Immunol. 2007. PMID: 17304234 Review.

8

Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination.

Velu V, Kannanganat S, Ibegbu C, Chennareddi L, Villinger F, Freeman GJ, Ahmed R, Amara RR. Velu V, et al. Among authors: ahmed r. J Virol. 2007 Jun;81(11):5819-28. doi: 10.1128/JVI.00024-07. Epub 2007 Mar 21. J Virol. 2007. PMID: 17376899 Free PMC article.

9

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection.

Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, Larsen CP, Ahmed R. Mueller SN, et al. Among authors: ahmed r. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15430-5. doi: 10.1073/pnas.0702579104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878315 Free PMC article.

10

Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.

Ha SJ, Mueller SN, Wherry EJ, Barber DL, Aubert RD, Sharpe AH, Freeman GJ, Ahmed R. Ha SJ, et al. Among authors: ahmed r. J Exp Med. 2008 Mar 17;205(3):543-55. doi: 10.1084/jem.20071949. Epub 2008 Mar 10. J Exp Med. 2008. PMID: 18332181 Free PMC article.

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