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Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.
J Virol. 2014 Mar;88(5):2508-18. doi: 10.1128/JVI.02034-13. Epub 2013 Dec 18.
J Virol. 2014.
PMID: 24352453
Free PMC article.
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.
Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufmann DE, Walker BD, Ebert B, Haining WN.
Quigley M, et al. Among authors: zupkosky j.
Nat Med. 2010 Oct;16(10):1147-51. doi: 10.1038/nm.2232. Epub 2010 Oct 3.
Nat Med. 2010.
PMID: 20890291
Free PMC article.
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Responsiveness of HIV-specific CD4 T cells to PD-1 blockade.
Porichis F, Kwon DS, Zupkosky J, Tighe DP, McMullen A, Brockman MA, Pavlik DF, Rodriguez-Garcia M, Pereyra F, Freeman GJ, Kavanagh DG, Kaufmann DE.
Porichis F, et al. Among authors: zupkosky j.
Blood. 2011 Jul 28;118(4):965-74. doi: 10.1182/blood-2010-12-328070. Epub 2011 Jun 7.
Blood. 2011.
PMID: 21652684
Free PMC article.
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In vitro assay to evaluate the impact of immunoregulatory pathways on HIV-specific CD4 T cell effector function.
Porichis F, Hart MG, Zupkosky J, Barblu L, Kaufmann DE.
Porichis F, et al. Among authors: zupkosky j.
J Vis Exp. 2013 Oct 15;(80):e50821. doi: 10.3791/50821.
J Vis Exp. 2013.
PMID: 24193166
Free PMC article.
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Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.
Chetty S, Porichis F, Govender P, Zupkosky J, Ghebremichael M, Pillay M, Walker BD, Ndung'u T, Kaufmann DE, Kasprowicz VO.
Chetty S, et al. Among authors: zupkosky j.
AIDS. 2014 Nov 28;28(18):2671-6. doi: 10.1097/QAD.0000000000000437.
AIDS. 2014.
PMID: 25211438
Free PMC article.
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Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality.
Chetty S, Govender P, Zupkosky J, Pillay M, Ghebremichael M, Moosa MY, Ndung'u T, Porichis F, Kasprowicz VO.
Chetty S, et al. Among authors: zupkosky j.
PLoS One. 2015 Mar 17;10(3):e0118654. doi: 10.1371/journal.pone.0118654. eCollection 2015.
PLoS One. 2015.
PMID: 25781898
Free PMC article.
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Association of IL-10-promoter genetic variants with the rate of CD4 T-cell loss, IL-10 plasma levels, and breadth of cytotoxic T-cell lymphocyte response during chronic HIV-1 infection.
Naicker DD, Wang B, Losina E, Zupkosky J, Bryan S, Reddy S, Jaggernath M, Mokgoro M, Goulder PJ, Kaufmann DE, Ndung'u T.
Naicker DD, et al. Among authors: zupkosky j.
Clin Infect Dis. 2012 Jan 15;54(2):294-302. doi: 10.1093/cid/cir811. Epub 2011 Nov 18.
Clin Infect Dis. 2012.
PMID: 22100578
Free PMC article.
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