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A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. Among authors: fisher jk. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.
A stapled BID BH3 helix directly binds and activates BAX.
Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ. Walensky LD, et al. Mol Cell. 2006 Oct 20;24(2):199-210. doi: 10.1016/j.molcel.2006.08.020. Mol Cell. 2006. PMID: 17052454 Free article.
Dual role of proapoptotic BAD in insulin secretion and beta cell survival.
Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ. Danial NN, et al. Among authors: fisher jk. Nat Med. 2008 Feb;14(2):144-53. doi: 10.1038/nm1717. Epub 2008 Jan 27. Nat Med. 2008. PMID: 18223655 Free PMC article.
VDAC2 inhibits BAK activation and mitochondrial apoptosis.
Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ. Cheng EH, et al. Among authors: fisher jk. Science. 2003 Jul 25;301(5632):513-7. doi: 10.1126/science.1083995. Science. 2003. PMID: 12881569
69 results