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Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial.
Parkinson Study Group SURE-PD Investigators; Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D, Rudolph A, Shoulson I, Tennis MK, Espay AJ, Gartner M, Hung A, Bwala G, Lenehan R, Encarnacion E, Ainslie M, Castillo R, Togasaki D, Barles G, Friedman JH, Niles L, Carter JH, Murray M, Goetz CG, Jaglin J, Ahmed A, Russell DS, Cotto C, Goudreau JL, Russell D, Parashos SA, Ede P, Saint-Hilaire MH, Thomas CA, James R, Stacy MA, Johnson J, Gauger L, Antonelle de Marcaida J, Thurlow S, Isaacson SH, Carvajal L, Rao J, Cook M, Hope-Porche C, McClurg L, Grasso DL, Logan R, Orme C, Ross T, Brocht AF, Constantinescu R, Sharma S, Venuto C, Weber J, Eaton K. Parkinson Study Group SURE-PD Investigators, et al. Among authors: logan r. JAMA Neurol. 2014 Feb;71(2):141-50. doi: 10.1001/jamaneurol.2013.5528. JAMA Neurol. 2014. PMID: 24366103 Free PMC article. Clinical Trial.
Higher urate in LRRK2 mutation carriers resistant to Parkinson disease.
Bakshi R, Macklin EA, Logan R, Zorlu MM, Xia N, Crotty GF, Zhang E, Chen X, Ascherio A, Schwarzschild MA. Bakshi R, et al. Among authors: logan r. Ann Neurol. 2019 Apr;85(4):593-599. doi: 10.1002/ana.25436. Epub 2019 Mar 3. Ann Neurol. 2019. PMID: 30761591
Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial.
Schwarzschild MA, Macklin EA, Bakshi R, Battacharyya S, Logan R, Espay AJ, Hung AY, Bwala G, Goetz CG, Russell DS, Goudreau JL, Parashos SA, Saint-Hilaire MH, Rudolph A, Hare JM, Curhan GC, Ascherio A; Parkinson Study Group SURE-PD Investigators. Schwarzschild MA, et al. Among authors: logan r. Neurology. 2019 Oct 1;93(14):e1328-e1338. doi: 10.1212/WNL.0000000000008194. Epub 2019 Sep 4. Neurology. 2019. PMID: 31484712 Free PMC article. Clinical Trial.
Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease.
Chen X, Umeh CC, Tainsh RE, Feng DD, Maguire M, Zuo F, Rahimian M, Logan R, Wang X, Ascherio A, Macklin EA, Buys ES, Schwarzschild MA; Parkinson Study Group (PSG) The Safety of Urate Elevation in Parkinson's Disease (SURE-PD) investigators. Chen X, et al. Among authors: logan r. EBioMedicine. 2018 Nov;37:259-268. doi: 10.1016/j.ebiom.2018.10.039. Epub 2018 Nov 8. EBioMedicine. 2018. PMID: 30415890 Free PMC article. Clinical Trial.
The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival.
Chen X, Chen H, Cai W, Maguire M, Ya B, Zuo F, Logan R, Li H, Robinson K, Vanderburg CR, Yu Y, Wang Y, Fisher DE, Schwarzschild MA. Chen X, et al. Among authors: logan r. Ann Neurol. 2017 Mar;81(3):395-406. doi: 10.1002/ana.24852. Epub 2017 Jan 23. Ann Neurol. 2017. PMID: 28019657 Free PMC article.
1,030 results